Coordination of endothelial cell positioning and fate specification by the epicardium

It remains unclear how spatial information controls endothelial cell identity and behavior in the developing heart. Here the authors perform single cell RNA sequencing at key developmental timepoints in mice to interrogate cellular contributions to coronary vessel patterning and maturation in the ep...

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Autores principales: Pearl Quijada, Michael A. Trembley, Adwiteeya Misra, Jacquelyn A. Myers, Cameron D. Baker, Marta Pérez-Hernández, Jason R. Myers, Ronald A. Dirkx, Ethan David Cohen, Mario Delmar, John M. Ashton, Eric M. Small
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/490625a4402947fb92af5dfa14861595
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Sumario:It remains unclear how spatial information controls endothelial cell identity and behavior in the developing heart. Here the authors perform single cell RNA sequencing at key developmental timepoints in mice to interrogate cellular contributions to coronary vessel patterning and maturation in the epicardium.