Coordination of endothelial cell positioning and fate specification by the epicardium

It remains unclear how spatial information controls endothelial cell identity and behavior in the developing heart. Here the authors perform single cell RNA sequencing at key developmental timepoints in mice to interrogate cellular contributions to coronary vessel patterning and maturation in the ep...

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Autores principales: Pearl Quijada, Michael A. Trembley, Adwiteeya Misra, Jacquelyn A. Myers, Cameron D. Baker, Marta Pérez-Hernández, Jason R. Myers, Ronald A. Dirkx, Ethan David Cohen, Mario Delmar, John M. Ashton, Eric M. Small
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/490625a4402947fb92af5dfa14861595
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spelling oai:doaj.org-article:490625a4402947fb92af5dfa148615952021-12-02T18:33:59ZCoordination of endothelial cell positioning and fate specification by the epicardium10.1038/s41467-021-24414-z2041-1723https://doaj.org/article/490625a4402947fb92af5dfa148615952021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24414-zhttps://doaj.org/toc/2041-1723It remains unclear how spatial information controls endothelial cell identity and behavior in the developing heart. Here the authors perform single cell RNA sequencing at key developmental timepoints in mice to interrogate cellular contributions to coronary vessel patterning and maturation in the epicardium.Pearl QuijadaMichael A. TrembleyAdwiteeya MisraJacquelyn A. MyersCameron D. BakerMarta Pérez-HernándezJason R. MyersRonald A. DirkxEthan David CohenMario DelmarJohn M. AshtonEric M. SmallNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pearl Quijada
Michael A. Trembley
Adwiteeya Misra
Jacquelyn A. Myers
Cameron D. Baker
Marta Pérez-Hernández
Jason R. Myers
Ronald A. Dirkx
Ethan David Cohen
Mario Delmar
John M. Ashton
Eric M. Small
Coordination of endothelial cell positioning and fate specification by the epicardium
description It remains unclear how spatial information controls endothelial cell identity and behavior in the developing heart. Here the authors perform single cell RNA sequencing at key developmental timepoints in mice to interrogate cellular contributions to coronary vessel patterning and maturation in the epicardium.
format article
author Pearl Quijada
Michael A. Trembley
Adwiteeya Misra
Jacquelyn A. Myers
Cameron D. Baker
Marta Pérez-Hernández
Jason R. Myers
Ronald A. Dirkx
Ethan David Cohen
Mario Delmar
John M. Ashton
Eric M. Small
author_facet Pearl Quijada
Michael A. Trembley
Adwiteeya Misra
Jacquelyn A. Myers
Cameron D. Baker
Marta Pérez-Hernández
Jason R. Myers
Ronald A. Dirkx
Ethan David Cohen
Mario Delmar
John M. Ashton
Eric M. Small
author_sort Pearl Quijada
title Coordination of endothelial cell positioning and fate specification by the epicardium
title_short Coordination of endothelial cell positioning and fate specification by the epicardium
title_full Coordination of endothelial cell positioning and fate specification by the epicardium
title_fullStr Coordination of endothelial cell positioning and fate specification by the epicardium
title_full_unstemmed Coordination of endothelial cell positioning and fate specification by the epicardium
title_sort coordination of endothelial cell positioning and fate specification by the epicardium
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/490625a4402947fb92af5dfa14861595
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