Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk

In neurons and glia, glutamate transporters catalyse the reuptake of this neurotransmitter by coupling it with cation transport. Here the authors combine X-ray crystallography and molecular dynamics simulations of the archeal glutamate transporter GltTkto get insight into the coupled transport mecha...

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Bibliographic Details
Main Authors: Albert Guskov, Sonja Jensen, Ignacio Faustino, Siewert J. Marrink, Dirk Jan Slotboom
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/49168b729b4f4cfb964f5e76eb8a8c28
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