Store-independent modulation of Ca2+ entry through Orai by Septin 7

Orai channels are well known to mediate store-operated calcium entry. Here authors show that in neurons of the Drosophilaflight circuit, Septin 7 acts as a negative regulator of Orai channels, surprisingly, by modulating store-independent calcium entry through Orai.

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Autores principales:	Bipan Kumar Deb, Trayambak Pathak, Gaiti Hasan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4926676738684a7aa119800e925c546c
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spelling	oai:doaj.org-article:4926676738684a7aa119800e925c546c2021-12-02T16:58:11ZStore-independent modulation of Ca2+ entry through Orai by Septin 710.1038/ncomms117512041-1723https://doaj.org/article/4926676738684a7aa119800e925c546c2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11751https://doaj.org/toc/2041-1723Orai channels are well known to mediate store-operated calcium entry. Here authors show that in neurons of the Drosophilaflight circuit, Septin 7 acts as a negative regulator of Orai channels, surprisingly, by modulating store-independent calcium entry through Orai.Bipan Kumar DebTrayambak PathakGaiti HasanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bipan Kumar Deb Trayambak Pathak Gaiti Hasan Store-independent modulation of Ca2+ entry through Orai by Septin 7
description	Orai channels are well known to mediate store-operated calcium entry. Here authors show that in neurons of the Drosophilaflight circuit, Septin 7 acts as a negative regulator of Orai channels, surprisingly, by modulating store-independent calcium entry through Orai.
format	article
author	Bipan Kumar Deb Trayambak Pathak Gaiti Hasan
author_facet	Bipan Kumar Deb Trayambak Pathak Gaiti Hasan
author_sort	Bipan Kumar Deb
title	Store-independent modulation of Ca2+ entry through Orai by Septin 7
title_short	Store-independent modulation of Ca2+ entry through Orai by Septin 7
title_full	Store-independent modulation of Ca2+ entry through Orai by Septin 7
title_fullStr	Store-independent modulation of Ca2+ entry through Orai by Septin 7
title_full_unstemmed	Store-independent modulation of Ca2+ entry through Orai by Septin 7
title_sort	store-independent modulation of ca2+ entry through orai by septin 7
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4926676738684a7aa119800e925c546c
work_keys_str_mv	AT bipankumardeb storeindependentmodulationofca2entrythroughoraibyseptin7 AT trayambakpathak storeindependentmodulationofca2entrythroughoraibyseptin7 AT gaitihasan storeindependentmodulationofca2entrythroughoraibyseptin7
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Store-independent modulation of Ca2+ entry through Orai by Septin 7

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