Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53.

Infections with high-risk human papillomaviruses (HPVs) are causally involved in the development of anogenital cancer. HPVs apparently evade the innate immune response of their host cells by dysregulating immunomodulatory factors such as cytokines and chemokines, thereby creating a microenvironment...

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Autores principales: Martina Niebler, Xu Qian, Daniela Höfler, Vlada Kogosov, Jittranan Kaewprag, Andreas M Kaufmann, Regina Ly, Gerd Böhmer, Rainer Zawatzky, Frank Rösl, Bladimiro Rincon-Orozco
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/49270fd9f5114dcba3631f52864bd6ae
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