A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.

Guardado en:
Detalles Bibliográficos
Autores principales: Alenka Čopič, Sandra Antoine-Bally, Manuel Giménez-Andrés, César La Torre Garay, Bruno Antonny, Marco M. Manni, Sophie Pagnotta, Jeanne Guihot, Catherine L. Jackson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/492f328f8d8144b1b134824fe07962c6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:492f328f8d8144b1b134824fe07962c6
record_format dspace
spelling oai:doaj.org-article:492f328f8d8144b1b134824fe07962c62021-12-02T17:32:02ZA giant amphipathic helix from a perilipin that is adapted for coating lipid droplets10.1038/s41467-018-03717-82041-1723https://doaj.org/article/492f328f8d8144b1b134824fe07962c62018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03717-8https://doaj.org/toc/2041-1723Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.Alenka ČopičSandra Antoine-BallyManuel Giménez-AndrésCésar La Torre GarayBruno AntonnyMarco M. ManniSophie PagnottaJeanne GuihotCatherine L. JacksonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alenka Čopič
Sandra Antoine-Bally
Manuel Giménez-Andrés
César La Torre Garay
Bruno Antonny
Marco M. Manni
Sophie Pagnotta
Jeanne Guihot
Catherine L. Jackson
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
description Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.
format article
author Alenka Čopič
Sandra Antoine-Bally
Manuel Giménez-Andrés
César La Torre Garay
Bruno Antonny
Marco M. Manni
Sophie Pagnotta
Jeanne Guihot
Catherine L. Jackson
author_facet Alenka Čopič
Sandra Antoine-Bally
Manuel Giménez-Andrés
César La Torre Garay
Bruno Antonny
Marco M. Manni
Sophie Pagnotta
Jeanne Guihot
Catherine L. Jackson
author_sort Alenka Čopič
title A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
title_short A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
title_full A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
title_fullStr A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
title_full_unstemmed A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
title_sort giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/492f328f8d8144b1b134824fe07962c6
work_keys_str_mv AT alenkacopic agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT sandraantoinebally agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT manuelgimenezandres agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT cesarlatorregaray agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT brunoantonny agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT marcommanni agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT sophiepagnotta agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT jeanneguihot agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT catherineljackson agiantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT alenkacopic giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT sandraantoinebally giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT manuelgimenezandres giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT cesarlatorregaray giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT brunoantonny giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT marcommanni giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT sophiepagnotta giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT jeanneguihot giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
AT catherineljackson giantamphipathichelixfromaperilipinthatisadaptedforcoatinglipiddroplets
_version_ 1718380426920198144