A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/492f328f8d8144b1b134824fe07962c6 |
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oai:doaj.org-article:492f328f8d8144b1b134824fe07962c62021-12-02T17:32:02ZA giant amphipathic helix from a perilipin that is adapted for coating lipid droplets10.1038/s41467-018-03717-82041-1723https://doaj.org/article/492f328f8d8144b1b134824fe07962c62018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03717-8https://doaj.org/toc/2041-1723Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.Alenka ČopičSandra Antoine-BallyManuel Giménez-AndrésCésar La Torre GarayBruno AntonnyMarco M. ManniSophie PagnottaJeanne GuihotCatherine L. JacksonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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Science Q Alenka Čopič Sandra Antoine-Bally Manuel Giménez-Andrés César La Torre Garay Bruno Antonny Marco M. Manni Sophie Pagnotta Jeanne Guihot Catherine L. Jackson A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
description |
Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core. |
format |
article |
author |
Alenka Čopič Sandra Antoine-Bally Manuel Giménez-Andrés César La Torre Garay Bruno Antonny Marco M. Manni Sophie Pagnotta Jeanne Guihot Catherine L. Jackson |
author_facet |
Alenka Čopič Sandra Antoine-Bally Manuel Giménez-Andrés César La Torre Garay Bruno Antonny Marco M. Manni Sophie Pagnotta Jeanne Guihot Catherine L. Jackson |
author_sort |
Alenka Čopič |
title |
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
title_short |
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
title_full |
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
title_fullStr |
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
title_full_unstemmed |
A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
title_sort |
giant amphipathic helix from a perilipin that is adapted for coating lipid droplets |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/492f328f8d8144b1b134824fe07962c6 |
work_keys_str_mv |
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