A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid droplet targeting and stabilization of the oil core.
Guardado en:
Autores principales: | Alenka Čopič, Sandra Antoine-Bally, Manuel Giménez-Andrés, César La Torre Garay, Bruno Antonny, Marco M. Manni, Sophie Pagnotta, Jeanne Guihot, Catherine L. Jackson |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/492f328f8d8144b1b134824fe07962c6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
por: Meredith H Wilson, et al.
Publicado: (2021) -
Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells.
por: Hans Heid, et al.
Publicado: (2013) -
The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation.
por: Chai Ann Ng, et al.
Publicado: (2011) -
Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.
por: Daniel Aberle, et al.
Publicado: (2014) -
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis
por: Wanlu Zhang, et al.
Publicado: (2021)