Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated wi...
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Nature Portfolio
2020
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oai:doaj.org-article:4947118a87984a6abb9c9a6e884df1b92021-12-02T16:35:00ZIntegrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate10.1038/s41467-020-17880-42041-1723https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b92020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17880-4https://doaj.org/toc/2041-1723Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated with gallbladder cancer.Akhilesh PandeyEric W. StawiskiSteffen DurinckHarsha GowdaLeonard D. GoldsteinMustafa A. BarbhuiyaMarkus S. SchröderSreelakshmi K. SreenivasamurthySun-Whe KimSameer PhalkeKushal SuryamohanKayla LeePapia ChakrabortyVasumathi KodeXiaoshan ShiAditi ChatterjeeKeshava DattaAafaque A. KhanTejaswini SubbannayyaJing WangSubhra ChaudhuriSanjiv GuptaBraj Raj ShrivastavBijay S. JaiswalSatish S. PoojaryShushruta BhuniaPatricia GarciaCarolina BizamaLorena RosaWooil KwonHongbeom KimYoungmin HanThakur Deen YadavVedam L. RamprasadAmitabha ChaudhuriZora ModrusanJuan Carlos RoaPramod Kumar TiwariJin-Young JangSomasekar SeshagiriNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Akhilesh Pandey Eric W. Stawiski Steffen Durinck Harsha Gowda Leonard D. Goldstein Mustafa A. Barbhuiya Markus S. Schröder Sreelakshmi K. Sreenivasamurthy Sun-Whe Kim Sameer Phalke Kushal Suryamohan Kayla Lee Papia Chakraborty Vasumathi Kode Xiaoshan Shi Aditi Chatterjee Keshava Datta Aafaque A. Khan Tejaswini Subbannayya Jing Wang Subhra Chaudhuri Sanjiv Gupta Braj Raj Shrivastav Bijay S. Jaiswal Satish S. Poojary Shushruta Bhunia Patricia Garcia Carolina Bizama Lorena Rosa Wooil Kwon Hongbeom Kim Youngmin Han Thakur Deen Yadav Vedam L. Ramprasad Amitabha Chaudhuri Zora Modrusan Juan Carlos Roa Pramod Kumar Tiwari Jin-Young Jang Somasekar Seshagiri Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
description |
Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated with gallbladder cancer. |
format |
article |
author |
Akhilesh Pandey Eric W. Stawiski Steffen Durinck Harsha Gowda Leonard D. Goldstein Mustafa A. Barbhuiya Markus S. Schröder Sreelakshmi K. Sreenivasamurthy Sun-Whe Kim Sameer Phalke Kushal Suryamohan Kayla Lee Papia Chakraborty Vasumathi Kode Xiaoshan Shi Aditi Chatterjee Keshava Datta Aafaque A. Khan Tejaswini Subbannayya Jing Wang Subhra Chaudhuri Sanjiv Gupta Braj Raj Shrivastav Bijay S. Jaiswal Satish S. Poojary Shushruta Bhunia Patricia Garcia Carolina Bizama Lorena Rosa Wooil Kwon Hongbeom Kim Youngmin Han Thakur Deen Yadav Vedam L. Ramprasad Amitabha Chaudhuri Zora Modrusan Juan Carlos Roa Pramod Kumar Tiwari Jin-Young Jang Somasekar Seshagiri |
author_facet |
Akhilesh Pandey Eric W. Stawiski Steffen Durinck Harsha Gowda Leonard D. Goldstein Mustafa A. Barbhuiya Markus S. Schröder Sreelakshmi K. Sreenivasamurthy Sun-Whe Kim Sameer Phalke Kushal Suryamohan Kayla Lee Papia Chakraborty Vasumathi Kode Xiaoshan Shi Aditi Chatterjee Keshava Datta Aafaque A. Khan Tejaswini Subbannayya Jing Wang Subhra Chaudhuri Sanjiv Gupta Braj Raj Shrivastav Bijay S. Jaiswal Satish S. Poojary Shushruta Bhunia Patricia Garcia Carolina Bizama Lorena Rosa Wooil Kwon Hongbeom Kim Youngmin Han Thakur Deen Yadav Vedam L. Ramprasad Amitabha Chaudhuri Zora Modrusan Juan Carlos Roa Pramod Kumar Tiwari Jin-Young Jang Somasekar Seshagiri |
author_sort |
Akhilesh Pandey |
title |
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
title_short |
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
title_full |
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
title_fullStr |
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
title_full_unstemmed |
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate |
title_sort |
integrated genomic analysis reveals mutated elf3 as a potential gallbladder cancer vaccine candidate |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b9 |
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