Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated wi...

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Autores principales: Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda, Leonard D. Goldstein, Mustafa A. Barbhuiya, Markus S. Schröder, Sreelakshmi K. Sreenivasamurthy, Sun-Whe Kim, Sameer Phalke, Kushal Suryamohan, Kayla Lee, Papia Chakraborty, Vasumathi Kode, Xiaoshan Shi, Aditi Chatterjee, Keshava Datta, Aafaque A. Khan, Tejaswini Subbannayya, Jing Wang, Subhra Chaudhuri, Sanjiv Gupta, Braj Raj Shrivastav, Bijay S. Jaiswal, Satish S. Poojary, Shushruta Bhunia, Patricia Garcia, Carolina Bizama, Lorena Rosa, Wooil Kwon, Hongbeom Kim, Youngmin Han, Thakur Deen Yadav, Vedam L. Ramprasad, Amitabha Chaudhuri, Zora Modrusan, Juan Carlos Roa, Pramod Kumar Tiwari, Jin-Young Jang, Somasekar Seshagiri
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b9
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spelling oai:doaj.org-article:4947118a87984a6abb9c9a6e884df1b92021-12-02T16:35:00ZIntegrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate10.1038/s41467-020-17880-42041-1723https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b92020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17880-4https://doaj.org/toc/2041-1723Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated with gallbladder cancer.Akhilesh PandeyEric W. StawiskiSteffen DurinckHarsha GowdaLeonard D. GoldsteinMustafa A. BarbhuiyaMarkus S. SchröderSreelakshmi K. SreenivasamurthySun-Whe KimSameer PhalkeKushal SuryamohanKayla LeePapia ChakrabortyVasumathi KodeXiaoshan ShiAditi ChatterjeeKeshava DattaAafaque A. KhanTejaswini SubbannayyaJing WangSubhra ChaudhuriSanjiv GuptaBraj Raj ShrivastavBijay S. JaiswalSatish S. PoojaryShushruta BhuniaPatricia GarciaCarolina BizamaLorena RosaWooil KwonHongbeom KimYoungmin HanThakur Deen YadavVedam L. RamprasadAmitabha ChaudhuriZora ModrusanJuan Carlos RoaPramod Kumar TiwariJin-Young JangSomasekar SeshagiriNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Akhilesh Pandey
Eric W. Stawiski
Steffen Durinck
Harsha Gowda
Leonard D. Goldstein
Mustafa A. Barbhuiya
Markus S. Schröder
Sreelakshmi K. Sreenivasamurthy
Sun-Whe Kim
Sameer Phalke
Kushal Suryamohan
Kayla Lee
Papia Chakraborty
Vasumathi Kode
Xiaoshan Shi
Aditi Chatterjee
Keshava Datta
Aafaque A. Khan
Tejaswini Subbannayya
Jing Wang
Subhra Chaudhuri
Sanjiv Gupta
Braj Raj Shrivastav
Bijay S. Jaiswal
Satish S. Poojary
Shushruta Bhunia
Patricia Garcia
Carolina Bizama
Lorena Rosa
Wooil Kwon
Hongbeom Kim
Youngmin Han
Thakur Deen Yadav
Vedam L. Ramprasad
Amitabha Chaudhuri
Zora Modrusan
Juan Carlos Roa
Pramod Kumar Tiwari
Jin-Young Jang
Somasekar Seshagiri
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
description Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated with gallbladder cancer.
format article
author Akhilesh Pandey
Eric W. Stawiski
Steffen Durinck
Harsha Gowda
Leonard D. Goldstein
Mustafa A. Barbhuiya
Markus S. Schröder
Sreelakshmi K. Sreenivasamurthy
Sun-Whe Kim
Sameer Phalke
Kushal Suryamohan
Kayla Lee
Papia Chakraborty
Vasumathi Kode
Xiaoshan Shi
Aditi Chatterjee
Keshava Datta
Aafaque A. Khan
Tejaswini Subbannayya
Jing Wang
Subhra Chaudhuri
Sanjiv Gupta
Braj Raj Shrivastav
Bijay S. Jaiswal
Satish S. Poojary
Shushruta Bhunia
Patricia Garcia
Carolina Bizama
Lorena Rosa
Wooil Kwon
Hongbeom Kim
Youngmin Han
Thakur Deen Yadav
Vedam L. Ramprasad
Amitabha Chaudhuri
Zora Modrusan
Juan Carlos Roa
Pramod Kumar Tiwari
Jin-Young Jang
Somasekar Seshagiri
author_facet Akhilesh Pandey
Eric W. Stawiski
Steffen Durinck
Harsha Gowda
Leonard D. Goldstein
Mustafa A. Barbhuiya
Markus S. Schröder
Sreelakshmi K. Sreenivasamurthy
Sun-Whe Kim
Sameer Phalke
Kushal Suryamohan
Kayla Lee
Papia Chakraborty
Vasumathi Kode
Xiaoshan Shi
Aditi Chatterjee
Keshava Datta
Aafaque A. Khan
Tejaswini Subbannayya
Jing Wang
Subhra Chaudhuri
Sanjiv Gupta
Braj Raj Shrivastav
Bijay S. Jaiswal
Satish S. Poojary
Shushruta Bhunia
Patricia Garcia
Carolina Bizama
Lorena Rosa
Wooil Kwon
Hongbeom Kim
Youngmin Han
Thakur Deen Yadav
Vedam L. Ramprasad
Amitabha Chaudhuri
Zora Modrusan
Juan Carlos Roa
Pramod Kumar Tiwari
Jin-Young Jang
Somasekar Seshagiri
author_sort Akhilesh Pandey
title Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
title_short Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
title_full Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
title_fullStr Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
title_full_unstemmed Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
title_sort integrated genomic analysis reveals mutated elf3 as a potential gallbladder cancer vaccine candidate
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b9
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