Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection

Host-parasite interactions during the exoerythrocytic stage of Plasmodium infection remains poorly understood. Using dual RNA-Seq, the authors show that human mucosal immunity protein mucin-13 is upregulated during Plasmodium hepatic-stage infection and marks infected cells independent of tested Pla...

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Autores principales:	Gregory M. LaMonte, Pamela Orjuela-Sanchez, Jaeson Calla, Lawrence T. Wang, Shangzhong Li, Justine Swann, Annie N. Cowell, Bing Yu Zou, Alyaa M. Abdel-Haleem Mohamed, Zaira Hellen Villa Galarce, Marta Moreno, Carlos Tong Rios, Joseph M. Vinetz, Nathan Lewis, Elizabeth A. Winzeler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4951c6ea139b4323a6d31d29038c5820
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spelling	oai:doaj.org-article:4951c6ea139b4323a6d31d29038c58202021-12-02T15:35:13ZDual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection10.1038/s41467-019-08349-02041-1723https://doaj.org/article/4951c6ea139b4323a6d31d29038c58202019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08349-0https://doaj.org/toc/2041-1723Host-parasite interactions during the exoerythrocytic stage of Plasmodium infection remains poorly understood. Using dual RNA-Seq, the authors show that human mucosal immunity protein mucin-13 is upregulated during Plasmodium hepatic-stage infection and marks infected cells independent of tested Plasmodium species.Gregory M. LaMontePamela Orjuela-SanchezJaeson CallaLawrence T. WangShangzhong LiJustine SwannAnnie N. CowellBing Yu ZouAlyaa M. Abdel-Haleem MohamedZaira Hellen Villa GalarceMarta MorenoCarlos Tong RiosJoseph M. VinetzNathan LewisElizabeth A. WinzelerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gregory M. LaMonte Pamela Orjuela-Sanchez Jaeson Calla Lawrence T. Wang Shangzhong Li Justine Swann Annie N. Cowell Bing Yu Zou Alyaa M. Abdel-Haleem Mohamed Zaira Hellen Villa Galarce Marta Moreno Carlos Tong Rios Joseph M. Vinetz Nathan Lewis Elizabeth A. Winzeler Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
description	Host-parasite interactions during the exoerythrocytic stage of Plasmodium infection remains poorly understood. Using dual RNA-Seq, the authors show that human mucosal immunity protein mucin-13 is upregulated during Plasmodium hepatic-stage infection and marks infected cells independent of tested Plasmodium species.
format	article
author	Gregory M. LaMonte Pamela Orjuela-Sanchez Jaeson Calla Lawrence T. Wang Shangzhong Li Justine Swann Annie N. Cowell Bing Yu Zou Alyaa M. Abdel-Haleem Mohamed Zaira Hellen Villa Galarce Marta Moreno Carlos Tong Rios Joseph M. Vinetz Nathan Lewis Elizabeth A. Winzeler
author_facet	Gregory M. LaMonte Pamela Orjuela-Sanchez Jaeson Calla Lawrence T. Wang Shangzhong Li Justine Swann Annie N. Cowell Bing Yu Zou Alyaa M. Abdel-Haleem Mohamed Zaira Hellen Villa Galarce Marta Moreno Carlos Tong Rios Joseph M. Vinetz Nathan Lewis Elizabeth A. Winzeler
author_sort	Gregory M. LaMonte
title	Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
title_short	Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
title_full	Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
title_fullStr	Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
title_full_unstemmed	Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
title_sort	dual rna-seq identifies human mucosal immunity protein mucin-13 as a hallmark of plasmodium exoerythrocytic infection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4951c6ea139b4323a6d31d29038c5820
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Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection

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