Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells

Innate lymphoid cells (ILCs) are important regulators of biological processes. Here the authors combine multiplexed imaging and computational pipelines to reveal tonsillar IRF4+ ILC3s, and to identify conserved stromal landmarks for ILC localization, thereby providing a platform for future ILC studi...

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Autores principales:	Anna Pascual-Reguant, Ralf Köhler, Ronja Mothes, Sandy Bauherr, Daniela C. Hernández, Ralf Uecker, Karolin Holzwarth, Katja Kotsch, Maximilian Seidl, Lars Philipsen, Werner Müller, Chiara Romagnani, Raluca Niesner, Anja E. Hauser
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4955d81086f14f0f900732deb328839a
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spelling	oai:doaj.org-article:4955d81086f14f0f900732deb328839a2021-12-02T17:04:54ZMultiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells10.1038/s41467-021-21994-82041-1723https://doaj.org/article/4955d81086f14f0f900732deb328839a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21994-8https://doaj.org/toc/2041-1723Innate lymphoid cells (ILCs) are important regulators of biological processes. Here the authors combine multiplexed imaging and computational pipelines to reveal tonsillar IRF4+ ILC3s, and to identify conserved stromal landmarks for ILC localization, thereby providing a platform for future ILC studies.Anna Pascual-ReguantRalf KöhlerRonja MothesSandy BauherrDaniela C. HernándezRalf UeckerKarolin HolzwarthKatja KotschMaximilian SeidlLars PhilipsenWerner MüllerChiara RomagnaniRaluca NiesnerAnja E. HauserNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna Pascual-Reguant Ralf Köhler Ronja Mothes Sandy Bauherr Daniela C. Hernández Ralf Uecker Karolin Holzwarth Katja Kotsch Maximilian Seidl Lars Philipsen Werner Müller Chiara Romagnani Raluca Niesner Anja E. Hauser Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
description	Innate lymphoid cells (ILCs) are important regulators of biological processes. Here the authors combine multiplexed imaging and computational pipelines to reveal tonsillar IRF4+ ILC3s, and to identify conserved stromal landmarks for ILC localization, thereby providing a platform for future ILC studies.
format	article
author	Anna Pascual-Reguant Ralf Köhler Ronja Mothes Sandy Bauherr Daniela C. Hernández Ralf Uecker Karolin Holzwarth Katja Kotsch Maximilian Seidl Lars Philipsen Werner Müller Chiara Romagnani Raluca Niesner Anja E. Hauser
author_facet	Anna Pascual-Reguant Ralf Köhler Ronja Mothes Sandy Bauherr Daniela C. Hernández Ralf Uecker Karolin Holzwarth Katja Kotsch Maximilian Seidl Lars Philipsen Werner Müller Chiara Romagnani Raluca Niesner Anja E. Hauser
author_sort	Anna Pascual-Reguant
title	Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
title_short	Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
title_full	Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
title_fullStr	Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
title_full_unstemmed	Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
title_sort	multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4955d81086f14f0f900732deb328839a
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Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells

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