HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.

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Autores principales:	Sebastian Fritzwanker, Lionel Moulédous, Catherine Mollereau, Carine Froment, Odile Burlet-Schiltz, Felix Effah, Alexis Bailey, Mariana Spetea, Rainer K. Reinscheid, Stefan Schulz, Andrea Kliewer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/495c33f2d6324ceca45d00dab8a2f7bb
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spelling	oai:doaj.org-article:495c33f2d6324ceca45d00dab8a2f7bb2021-12-02T18:02:22ZHA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants10.1038/s42003-021-02580-62399-3642https://doaj.org/article/495c33f2d6324ceca45d00dab8a2f7bb2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02580-6https://doaj.org/toc/2399-3642Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.Sebastian FritzwankerLionel MoulédousCatherine MollereauCarine FromentOdile Burlet-SchiltzFelix EffahAlexis BaileyMariana SpeteaRainer K. ReinscheidStefan SchulzAndrea KliewerNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Sebastian Fritzwanker Lionel Moulédous Catherine Mollereau Carine Froment Odile Burlet-Schiltz Felix Effah Alexis Bailey Mariana Spetea Rainer K. Reinscheid Stefan Schulz Andrea Kliewer HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
description	Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.
format	article
author	Sebastian Fritzwanker Lionel Moulédous Catherine Mollereau Carine Froment Odile Burlet-Schiltz Felix Effah Alexis Bailey Mariana Spetea Rainer K. Reinscheid Stefan Schulz Andrea Kliewer
author_facet	Sebastian Fritzwanker Lionel Moulédous Catherine Mollereau Carine Froment Odile Burlet-Schiltz Felix Effah Alexis Bailey Mariana Spetea Rainer K. Reinscheid Stefan Schulz Andrea Kliewer
author_sort	Sebastian Fritzwanker
title	HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
title_short	HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
title_full	HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
title_fullStr	HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
title_full_unstemmed	HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
title_sort	ha-mop knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/495c33f2d6324ceca45d00dab8a2f7bb
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HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

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