HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.
Saved in:
Main Authors: | Sebastian Fritzwanker, Lionel Moulédous, Catherine Mollereau, Carine Froment, Odile Burlet-Schiltz, Felix Effah, Alexis Bailey, Mariana Spetea, Rainer K. Reinscheid, Stefan Schulz, Andrea Kliewer |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/495c33f2d6324ceca45d00dab8a2f7bb |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects
by: A. Kliewer, et al.
Published: (2019) -
How μ-opioid receptor recognizes fentanyl
by: Quynh N. Vo, et al.
Published: (2021) -
μ-opioid receptor system mediates reward processing in humans
by: Lauri Nummenmaa, et al.
Published: (2018) -
Functional characteristics of the naked mole rat μ-opioid receptor.
by: Melanie Busch-Dienstfertig, et al.
Published: (2013) -
EFFECT OF MOP-DRYING ON BODY TEMPERATURE OF PORCINE NEONATES
by: S. Pan
Published: (1995)