Molecular evolution and the decline of purifying selection with age

A fundamental principle of evolutionary theory is that the force of natural selection is weaker on traits expressed late in life relative to traits expressed early. Here, the authors find strong and consistent patterns of molecular evolution reflecting this principle in four species of animals, incl...

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Autores principales:	Changde Cheng, Mark Kirkpatrick
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/496115b4305e44228846a42dfbc80f54
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spelling	oai:doaj.org-article:496115b4305e44228846a42dfbc80f542021-12-02T15:36:11ZMolecular evolution and the decline of purifying selection with age10.1038/s41467-021-22981-92041-1723https://doaj.org/article/496115b4305e44228846a42dfbc80f542021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22981-9https://doaj.org/toc/2041-1723A fundamental principle of evolutionary theory is that the force of natural selection is weaker on traits expressed late in life relative to traits expressed early. Here, the authors find strong and consistent patterns of molecular evolution reflecting this principle in four species of animals, including humans.Changde ChengMark KirkpatrickNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Changde Cheng Mark Kirkpatrick Molecular evolution and the decline of purifying selection with age
description	A fundamental principle of evolutionary theory is that the force of natural selection is weaker on traits expressed late in life relative to traits expressed early. Here, the authors find strong and consistent patterns of molecular evolution reflecting this principle in four species of animals, including humans.
format	article
author	Changde Cheng Mark Kirkpatrick
author_facet	Changde Cheng Mark Kirkpatrick
author_sort	Changde Cheng
title	Molecular evolution and the decline of purifying selection with age
title_short	Molecular evolution and the decline of purifying selection with age
title_full	Molecular evolution and the decline of purifying selection with age
title_fullStr	Molecular evolution and the decline of purifying selection with age
title_full_unstemmed	Molecular evolution and the decline of purifying selection with age
title_sort	molecular evolution and the decline of purifying selection with age
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/496115b4305e44228846a42dfbc80f54
work_keys_str_mv	AT changdecheng molecularevolutionandthedeclineofpurifyingselectionwithage AT markkirkpatrick molecularevolutionandthedeclineofpurifyingselectionwithage
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Molecular evolution and the decline of purifying selection with age

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