Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru

Abstract Salmonella Enteritidis, an important foodborne zoonosis, has a dramatically increased number of cases around the world. To explore the phylogenetic structure of Peruvian Salmonella Enteritidis strains and their relationship with an outbreak occurred in 2018, we analyzed a comprehensive stra...

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Autores principales:	Willi Quino, Junior Caro-Castro, Orson Mestanza, Carmen V. Hurtado, Maria L. Zamudio, Ronnie G. Gavilan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/496ca4a096034692bf6729a09c6f87bc
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spelling	oai:doaj.org-article:496ca4a096034692bf6729a09c6f87bc2021-12-02T12:42:27ZPhylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru10.1038/s41598-020-78808-y2045-2322https://doaj.org/article/496ca4a096034692bf6729a09c6f87bc2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78808-yhttps://doaj.org/toc/2045-2322Abstract Salmonella Enteritidis, an important foodborne zoonosis, has a dramatically increased number of cases around the world. To explore the phylogenetic structure of Peruvian Salmonella Enteritidis strains and their relationship with an outbreak occurred in 2018, we analyzed a comprehensive strains of S. Enteritidis received by the National Institute of Health during the period 2000–2018. A total of 180 strains were characterized by microbiological procedures, serotyping and whole genome sequencing. Based on genome sequences annotated, virulence factors and accessory genes were identified. Phylogenetic and population structure analysis were also analyzed based on SNPs. The phylogenetic analysis grouped the genomes into two well-supported clades that were consistent with population structure analysis. The clinical and food strains corresponding to the outbreak were included in the same cluster, which presented the sdhA gene, related to the increase of the virulence of this pathogen. The phylogenetic relationship of Peruvian S. Enteritidis suggests the presence of four S. enteritidis population with high epidemiological importance.Willi QuinoJunior Caro-CastroOrson MestanzaCarmen V. HurtadoMaria L. ZamudioRonnie G. GavilanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Willi Quino Junior Caro-Castro Orson Mestanza Carmen V. Hurtado Maria L. Zamudio Ronnie G. Gavilan Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
description	Abstract Salmonella Enteritidis, an important foodborne zoonosis, has a dramatically increased number of cases around the world. To explore the phylogenetic structure of Peruvian Salmonella Enteritidis strains and their relationship with an outbreak occurred in 2018, we analyzed a comprehensive strains of S. Enteritidis received by the National Institute of Health during the period 2000–2018. A total of 180 strains were characterized by microbiological procedures, serotyping and whole genome sequencing. Based on genome sequences annotated, virulence factors and accessory genes were identified. Phylogenetic and population structure analysis were also analyzed based on SNPs. The phylogenetic analysis grouped the genomes into two well-supported clades that were consistent with population structure analysis. The clinical and food strains corresponding to the outbreak were included in the same cluster, which presented the sdhA gene, related to the increase of the virulence of this pathogen. The phylogenetic relationship of Peruvian S. Enteritidis suggests the presence of four S. enteritidis population with high epidemiological importance.
format	article
author	Willi Quino Junior Caro-Castro Orson Mestanza Carmen V. Hurtado Maria L. Zamudio Ronnie G. Gavilan
author_facet	Willi Quino Junior Caro-Castro Orson Mestanza Carmen V. Hurtado Maria L. Zamudio Ronnie G. Gavilan
author_sort	Willi Quino
title	Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
title_short	Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
title_full	Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
title_fullStr	Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
title_full_unstemmed	Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru
title_sort	phylogenetic structure of salmonella enteritidis provides context for a foodborne outbreak in peru
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/496ca4a096034692bf6729a09c6f87bc
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_version_	1718393683997360128

Phylogenetic structure of Salmonella Enteritidis provides context for a foodborne outbreak in Peru

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