Digital immunoassay for biomarker concentration quantification using solid-state nanopores

The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating hormone from human serum.

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Autores principales:	Liqun He, Daniel R. Tessier, Kyle Briggs, Matthaios Tsangaris, Martin Charron, Erin M. McConnell, Dmytro Lomovtsev, Vincent Tabard-Cossa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/49741f2631fc4bbb81a308132e47132a
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spelling	oai:doaj.org-article:49741f2631fc4bbb81a308132e47132a2021-12-02T17:19:40ZDigital immunoassay for biomarker concentration quantification using solid-state nanopores10.1038/s41467-021-25566-82041-1723https://doaj.org/article/49741f2631fc4bbb81a308132e47132a2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25566-8https://doaj.org/toc/2041-1723The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating hormone from human serum.Liqun HeDaniel R. TessierKyle BriggsMatthaios TsangarisMartin CharronErin M. McConnellDmytro LomovtsevVincent Tabard-CossaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Liqun He Daniel R. Tessier Kyle Briggs Matthaios Tsangaris Martin Charron Erin M. McConnell Dmytro Lomovtsev Vincent Tabard-Cossa Digital immunoassay for biomarker concentration quantification using solid-state nanopores
description	The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating hormone from human serum.
format	article
author	Liqun He Daniel R. Tessier Kyle Briggs Matthaios Tsangaris Martin Charron Erin M. McConnell Dmytro Lomovtsev Vincent Tabard-Cossa
author_facet	Liqun He Daniel R. Tessier Kyle Briggs Matthaios Tsangaris Martin Charron Erin M. McConnell Dmytro Lomovtsev Vincent Tabard-Cossa
author_sort	Liqun He
title	Digital immunoassay for biomarker concentration quantification using solid-state nanopores
title_short	Digital immunoassay for biomarker concentration quantification using solid-state nanopores
title_full	Digital immunoassay for biomarker concentration quantification using solid-state nanopores
title_fullStr	Digital immunoassay for biomarker concentration quantification using solid-state nanopores
title_full_unstemmed	Digital immunoassay for biomarker concentration quantification using solid-state nanopores
title_sort	digital immunoassay for biomarker concentration quantification using solid-state nanopores
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/49741f2631fc4bbb81a308132e47132a
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Digital immunoassay for biomarker concentration quantification using solid-state nanopores

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