Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines

ABSTRACT Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens. We showed, through use of a CRISPR-Cas9 CD40 knockout, that the superantigens to...

Full description

Saved in:
Bibliographic Details
Main Authors: Patrick M. Schlievert, Michael P. Cahill, Bruce S. Hostager, Amanda J. Brosnahan, Aloysius J. Klingelhutz, Francoise A. Gourronc, Gail A. Bishop, Donald Y. M. Leung
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Online Access:https://doaj.org/article/49782844522c4c8c856aa6a48efa7298
Tags: Add Tag
No Tags, Be the first to tag this record!