Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin

Estrogen receptor alpha (ERα)-negative cells, which are enriched during endocrine therapy, are associated with metastatic relapse of breast cancer. Here the authors show that ERα inhibits breast cancer metastasis and suggest that ERα suppresses the amoeboid-like migration of breast cancer cells by u...

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Autores principales:	Yuan Gao, Zhaowei Wang, Qiang Hao, Weina Li, Yujin Xu, Juliang Zhang, Wangqian Zhang, Shuning Wang, Shuo Liu, Meng Li, Xiaochang Xue, Wei Zhang, Cun Zhang, Yingqi Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/497c98c28725493f9c831ab92207cd98
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spelling	oai:doaj.org-article:497c98c28725493f9c831ab92207cd982021-12-02T17:06:02ZLoss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin10.1038/ncomms144832041-1723https://doaj.org/article/497c98c28725493f9c831ab92207cd982017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14483https://doaj.org/toc/2041-1723Estrogen receptor alpha (ERα)-negative cells, which are enriched during endocrine therapy, are associated with metastatic relapse of breast cancer. Here the authors show that ERα inhibits breast cancer metastasis and suggest that ERα suppresses the amoeboid-like migration of breast cancer cells by upregulating vinculin.Yuan GaoZhaowei WangQiang HaoWeina LiYujin XuJuliang ZhangWangqian ZhangShuning WangShuo LiuMeng LiXiaochang XueWei ZhangCun ZhangYingqi ZhangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan Gao Zhaowei Wang Qiang Hao Weina Li Yujin Xu Juliang Zhang Wangqian Zhang Shuning Wang Shuo Liu Meng Li Xiaochang Xue Wei Zhang Cun Zhang Yingqi Zhang Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
description	Estrogen receptor alpha (ERα)-negative cells, which are enriched during endocrine therapy, are associated with metastatic relapse of breast cancer. Here the authors show that ERα inhibits breast cancer metastasis and suggest that ERα suppresses the amoeboid-like migration of breast cancer cells by upregulating vinculin.
format	article
author	Yuan Gao Zhaowei Wang Qiang Hao Weina Li Yujin Xu Juliang Zhang Wangqian Zhang Shuning Wang Shuo Liu Meng Li Xiaochang Xue Wei Zhang Cun Zhang Yingqi Zhang
author_facet	Yuan Gao Zhaowei Wang Qiang Hao Weina Li Yujin Xu Juliang Zhang Wangqian Zhang Shuning Wang Shuo Liu Meng Li Xiaochang Xue Wei Zhang Cun Zhang Yingqi Zhang
author_sort	Yuan Gao
title	Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
title_short	Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
title_full	Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
title_fullStr	Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
title_full_unstemmed	Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
title_sort	loss of erα induces amoeboid-like migration of breast cancer cells by downregulating vinculin
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/497c98c28725493f9c831ab92207cd98
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Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin

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