An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association

Pyogenic Granulomas (PG) are reactive hyperplastic lesions that are formed in relation to some chronic irritation, physical trauma or hormonal factors. The PG may present in various clinical and histological forms. These often present as a smooth lobulated exophytic lesions and at times may show a...

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Autores principales:	Aparna Dave, Manpreet Arora, Pulin Saluja, Ishita Singhal, Priyanka Singh
Formato:	article
Lenguaje:	EN
Publicado:	JCDR Research and Publications Private Limited 2021
Materias:	gingiva hormonal osteoid reactive lesions Medicine R
Acceso en línea:	https://doaj.org/article/497dca2d70a845e9b194b5b2ae449541
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spelling	oai:doaj.org-article:497dca2d70a845e9b194b5b2ae4495412021-11-14T06:47:37ZAn Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association10.7860/JCDR/2021/50298.153372249-782X0973-709Xhttps://doaj.org/article/497dca2d70a845e9b194b5b2ae4495412021-09-01T00:00:00Zhttps://www.jcdr.net/articles/PDF/15337/50298_CE[Ra1]_F(SHU)_PF1(JY_SHU)_PN(KM).pdfhttps://doaj.org/toc/2249-782Xhttps://doaj.org/toc/0973-709XPyogenic Granulomas (PG) are reactive hyperplastic lesions that are formed in relation to some chronic irritation, physical trauma or hormonal factors. The PG may present in various clinical and histological forms. These often present as a smooth lobulated exophytic lesions and at times may show a marked resemblance to Peripheral Ossifying Fibroma (POF). However, the characteristic histologic presentation helps in differentiating both the lesions. Microscopically, presence of ossification in pyogenic granuloma is not common and could possibly indicate an altered response of the connective tissue stroma. The present case report shows occurrence of pyogenic granuloma in a 12-year-old female which on histological examination not only exhibited proliferating blood vessels, endothelial cells and inflammatory cells which are typical features of pyogenic granuloma but also exhibited areas of ossifications which are not frequently encountered in PG. It is important to explore the underlying aetiological factors that could lead to formation of such ossifications. It has been suggested that pyogenic granuloma and peripheral ossifying fibroma could represent part of same spectrum of focal reactive lesions. However, it is still considered that these two lesions are separate clinical entities and the histologic presentations are different and unique to both of them.Aparna DaveManpreet AroraPulin SalujaIshita SinghalPriyanka SinghJCDR Research and Publications Private Limitedarticlegingivahormonalosteoidreactive lesionsMedicineRENJournal of Clinical and Diagnostic Research, Vol 15, Iss 9, Pp ZD01-ZD03 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	gingiva hormonal osteoid reactive lesions Medicine R
spellingShingle	gingiva hormonal osteoid reactive lesions Medicine R Aparna Dave Manpreet Arora Pulin Saluja Ishita Singhal Priyanka Singh An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
description	Pyogenic Granulomas (PG) are reactive hyperplastic lesions that are formed in relation to some chronic irritation, physical trauma or hormonal factors. The PG may present in various clinical and histological forms. These often present as a smooth lobulated exophytic lesions and at times may show a marked resemblance to Peripheral Ossifying Fibroma (POF). However, the characteristic histologic presentation helps in differentiating both the lesions. Microscopically, presence of ossification in pyogenic granuloma is not common and could possibly indicate an altered response of the connective tissue stroma. The present case report shows occurrence of pyogenic granuloma in a 12-year-old female which on histological examination not only exhibited proliferating blood vessels, endothelial cells and inflammatory cells which are typical features of pyogenic granuloma but also exhibited areas of ossifications which are not frequently encountered in PG. It is important to explore the underlying aetiological factors that could lead to formation of such ossifications. It has been suggested that pyogenic granuloma and peripheral ossifying fibroma could represent part of same spectrum of focal reactive lesions. However, it is still considered that these two lesions are separate clinical entities and the histologic presentations are different and unique to both of them.
format	article
author	Aparna Dave Manpreet Arora Pulin Saluja Ishita Singhal Priyanka Singh
author_facet	Aparna Dave Manpreet Arora Pulin Saluja Ishita Singhal Priyanka Singh
author_sort	Aparna Dave
title	An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
title_short	An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
title_full	An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
title_fullStr	An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
title_full_unstemmed	An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association
title_sort	insight into pyogenic granuloma with ossification: exploring a unique association
publisher	JCDR Research and Publications Private Limited
publishDate	2021
url	https://doaj.org/article/497dca2d70a845e9b194b5b2ae449541
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An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association

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