Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans

The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.

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Detalles Bibliográficos
Autores principales:	Clara L. Essmann, Daniel Martinez-Martinez, Rosina Pryor, Kit-Yi Leung, Kalaivani Bala Krishnan, Prudence Pokway Lui, Nicholas D. E. Greene, André E. X. Brown, Vijay M. Pawar, Mandayam A. Srinivasan, Filipe Cabreiro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/497f6a1f580e4f1db58b61849bc60df7
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spelling	oai:doaj.org-article:497f6a1f580e4f1db58b61849bc60df72021-12-02T17:33:12ZMechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans10.1038/s41467-020-14785-02041-1723https://doaj.org/article/497f6a1f580e4f1db58b61849bc60df72020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14785-0https://doaj.org/toc/2041-1723The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.Clara L. EssmannDaniel Martinez-MartinezRosina PryorKit-Yi LeungKalaivani Bala KrishnanPrudence Pokway LuiNicholas D. E. GreeneAndré E. X. BrownVijay M. PawarMandayam A. SrinivasanFilipe CabreiroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Clara L. Essmann Daniel Martinez-Martinez Rosina Pryor Kit-Yi Leung Kalaivani Bala Krishnan Prudence Pokway Lui Nicholas D. E. Greene André E. X. Brown Vijay M. Pawar Mandayam A. Srinivasan Filipe Cabreiro Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
description	The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.
format	article
author	Clara L. Essmann Daniel Martinez-Martinez Rosina Pryor Kit-Yi Leung Kalaivani Bala Krishnan Prudence Pokway Lui Nicholas D. E. Greene André E. X. Brown Vijay M. Pawar Mandayam A. Srinivasan Filipe Cabreiro
author_facet	Clara L. Essmann Daniel Martinez-Martinez Rosina Pryor Kit-Yi Leung Kalaivani Bala Krishnan Prudence Pokway Lui Nicholas D. E. Greene André E. X. Brown Vijay M. Pawar Mandayam A. Srinivasan Filipe Cabreiro
author_sort	Clara L. Essmann
title	Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
title_short	Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
title_full	Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
title_fullStr	Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
title_full_unstemmed	Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
title_sort	mechanical properties measured by atomic force microscopy define health biomarkers in ageing c. elegans
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/497f6a1f580e4f1db58b61849bc60df7
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Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans

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