Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
Abstract Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead to genomic instability and cancer predisposition. Here, we show that the protein lysine methyltr...
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Auteurs principaux: | , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/4981bcc1f4d943a6816b9de984a70298 |
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