The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance

The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance

In mammalian skeletal muscle, the DHPR functions as a voltage sensor to trigger muscle contraction and as a Ca2+ channel. Here the authors show that mice where Ca2+ influx through the DHPR is eliminated display no difference in skeletal muscle function, suggesting that the Ca2+ influx through this c...

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Autores principales: Anamika Dayal, Kai Schrötter, Yuan Pan, Karl Föhr, Werner Melzer, Manfred Grabner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4982215f05324a349f54db466bb3d76c
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spelling oai:doaj.org-article:4982215f05324a349f54db466bb3d76c2021-12-02T17:06:20ZThe Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance10.1038/s41467-017-00629-x2041-1723https://doaj.org/article/4982215f05324a349f54db466bb3d76c2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00629-xhttps://doaj.org/toc/2041-1723In mammalian skeletal muscle, the DHPR functions as a voltage sensor to trigger muscle contraction and as a Ca2+ channel. Here the authors show that mice where Ca2+ influx through the DHPR is eliminated display no difference in skeletal muscle function, suggesting that the Ca2+ influx through this channel is vestigial.Anamika DayalKai SchrötterYuan PanKarl FöhrWerner MelzerManfred GrabnerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anamika Dayal
Kai Schrötter
Yuan Pan
Karl Föhr
Werner Melzer
Manfred Grabner
The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
description In mammalian skeletal muscle, the DHPR functions as a voltage sensor to trigger muscle contraction and as a Ca2+ channel. Here the authors show that mice where Ca2+ influx through the DHPR is eliminated display no difference in skeletal muscle function, suggesting that the Ca2+ influx through this channel is vestigial.
format article
author Anamika Dayal
Kai Schrötter
Yuan Pan
Karl Föhr
Werner Melzer
Manfred Grabner
author_facet Anamika Dayal
Kai Schrötter
Yuan Pan
Karl Föhr
Werner Melzer
Manfred Grabner
author_sort Anamika Dayal
title The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
title_short The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
title_full The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
title_fullStr The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
title_full_unstemmed The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
title_sort ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4982215f05324a349f54db466bb3d76c
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