Drosophila Voltage-Gated Calcium Channel α1-Subunits Regulate Cardiac Function in the Aging Heart

Abstract Ion channels maintain numerous physiological functions and regulate signaling pathways. They are the key targets for cellular reactive oxygen species (ROS), acting as signaling switches between ROS and ionic homeostasis. We have carried out a paraquat (PQ) screen in Drosophila to identify i...

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Autores principales: Alexander Lam, Priyanka Karekar, Kajol Shah, Girija Hariharan, Michelle Fleyshman, Harmehak Kaur, Harpreet Singh, Shubha Gururaja Rao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/499678ac994a4f2d93c894804e6d6863
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