Hydrophobic collapse of trigger factor monomer in solution.

Trigger factor (TF) is a chaperone, found in bacterial cells and chloroplasts, that interacts with nascent polypeptide chains to suppress aggregation. While its crystal structure has been resolved, the solution structure and dynamics are largely unknown. We performed multiple molecular dynamics simu...

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Autores principales: Kushagra Singhal, Jocelyne Vreede, Alireza Mashaghi, Sander J Tans, Peter G Bolhuis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/499977ccd47d4c2e8e612025f5d20fe4
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