DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway

Abstract Collagen type VI (COL6) deposition occurs in various glomerular diseases, causing serious pathological damage like nodular lesions. However, the mechanisms underlying the deposition of COL6 remain unclear. In renal biopsy samples, immunohistochemical analyses revealed that COL6 and phosphor...

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Autores principales: Ai Fujii, Yumi Sunatani, Kengo Furuichi, Keiji Fujimoto, Hiroki Adachi, Kuniyoshi Iwabuchi, Hitoshi Yokoyama
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/49b1c77980ea411f91dae199ebe4dd2b
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