Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

The function of the Retinoblastoma (Rb) protein is regulated by its cellular environment. Here, the authors perform single cell RNA-sequencing during Drosophila eye development and identify the impact of an Rbf mutation, which sensitises specific cells to apoptosis by changing metabolism.

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Autores principales:	Majd M. Ariss, Abul B. M. M. K. Islam, Meg Critcher, Maria Paula Zappia, Maxim V. Frolov
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/49bd54d5f7f24dd9a90722ed635cd015
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spelling	oai:doaj.org-article:49bd54d5f7f24dd9a90722ed635cd0152021-12-02T15:33:36ZSingle cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant10.1038/s41467-018-07540-z2041-1723https://doaj.org/article/49bd54d5f7f24dd9a90722ed635cd0152018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07540-zhttps://doaj.org/toc/2041-1723The function of the Retinoblastoma (Rb) protein is regulated by its cellular environment. Here, the authors perform single cell RNA-sequencing during Drosophila eye development and identify the impact of an Rbf mutation, which sensitises specific cells to apoptosis by changing metabolism.Majd M. ArissAbul B. M. M. K. IslamMeg CritcherMaria Paula ZappiaMaxim V. FrolovNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Majd M. Ariss Abul B. M. M. K. Islam Meg Critcher Maria Paula Zappia Maxim V. Frolov Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
description	The function of the Retinoblastoma (Rb) protein is regulated by its cellular environment. Here, the authors perform single cell RNA-sequencing during Drosophila eye development and identify the impact of an Rbf mutation, which sensitises specific cells to apoptosis by changing metabolism.
format	article
author	Majd M. Ariss Abul B. M. M. K. Islam Meg Critcher Maria Paula Zappia Maxim V. Frolov
author_facet	Majd M. Ariss Abul B. M. M. K. Islam Meg Critcher Maria Paula Zappia Maxim V. Frolov
author_sort	Majd M. Ariss
title	Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
title_short	Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
title_full	Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
title_fullStr	Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
title_full_unstemmed	Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant
title_sort	single cell rna-sequencing identifies a metabolic aspect of apoptosis in rbf mutant
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/49bd54d5f7f24dd9a90722ed635cd015
work_keys_str_mv	AT majdmariss singlecellrnasequencingidentifiesametabolicaspectofapoptosisinrbfmutant AT abulbmmkislam singlecellrnasequencingidentifiesametabolicaspectofapoptosisinrbfmutant AT megcritcher singlecellrnasequencingidentifiesametabolicaspectofapoptosisinrbfmutant AT mariapaulazappia singlecellrnasequencingidentifiesametabolicaspectofapoptosisinrbfmutant AT maximvfrolov singlecellrnasequencingidentifiesametabolicaspectofapoptosisinrbfmutant
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Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

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