The lncRNA Neat1 promotes activation of inflammasomes in macrophages

The inflammasomes are important mediators of protective immunity by promoting inflammatory cytokine production and cell death. Here the authors show that a lncRNA, Neat1, is mobilized by inflammasome-activating signals to promote the assembly of several inflammasome complexes and cytokine maturation...

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Autores principales:	Pengfei Zhang, Limian Cao, Rongbin Zhou, Xiaolu Yang, Mian Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/49d1bba3ed8642708ffe6e7d44b7822d
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spelling	oai:doaj.org-article:49d1bba3ed8642708ffe6e7d44b7822d2021-12-02T15:35:36ZThe lncRNA Neat1 promotes activation of inflammasomes in macrophages10.1038/s41467-019-09482-62041-1723https://doaj.org/article/49d1bba3ed8642708ffe6e7d44b7822d2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09482-6https://doaj.org/toc/2041-1723The inflammasomes are important mediators of protective immunity by promoting inflammatory cytokine production and cell death. Here the authors show that a lncRNA, Neat1, is mobilized by inflammasome-activating signals to promote the assembly of several inflammasome complexes and cytokine maturation to regulate inflammation.Pengfei ZhangLimian CaoRongbin ZhouXiaolu YangMian WuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pengfei Zhang Limian Cao Rongbin Zhou Xiaolu Yang Mian Wu The lncRNA Neat1 promotes activation of inflammasomes in macrophages
description	The inflammasomes are important mediators of protective immunity by promoting inflammatory cytokine production and cell death. Here the authors show that a lncRNA, Neat1, is mobilized by inflammasome-activating signals to promote the assembly of several inflammasome complexes and cytokine maturation to regulate inflammation.
format	article
author	Pengfei Zhang Limian Cao Rongbin Zhou Xiaolu Yang Mian Wu
author_facet	Pengfei Zhang Limian Cao Rongbin Zhou Xiaolu Yang Mian Wu
author_sort	Pengfei Zhang
title	The lncRNA Neat1 promotes activation of inflammasomes in macrophages
title_short	The lncRNA Neat1 promotes activation of inflammasomes in macrophages
title_full	The lncRNA Neat1 promotes activation of inflammasomes in macrophages
title_fullStr	The lncRNA Neat1 promotes activation of inflammasomes in macrophages
title_full_unstemmed	The lncRNA Neat1 promotes activation of inflammasomes in macrophages
title_sort	lncrna neat1 promotes activation of inflammasomes in macrophages
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/49d1bba3ed8642708ffe6e7d44b7822d
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The lncRNA Neat1 promotes activation of inflammasomes in macrophages

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