Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments

Abstract In-vitro chemo-sensitivity experiments are an essential step in the early stages of cancer therapy development, but existing data analysis methods suffer from problems with fitting, do not permit assessment of uncertainty, and can give misleading estimates of cell growth inhibition. We pres...

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Autores principales: Yiyi Liu, Forrest W. Crawford
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/49deb11bf7ae455090e308a5693ea20e
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