Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in rats.

Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disease characterized by symptoms attributable to the death of striatal and cortical neurons. The molecular mechanisms mediating neuronal death in HD involve oxidative stress and mitochondrial dysfunction. Administ...

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Autores principales: Dirleise Colle, Danúbia Bonfanti Santos, Eduardo Luiz Gasnhar Moreira, Juliana Montagna Hartwig, Alessandra Antunes dos Santos, Luciana Teixeira Zimmermann, Mariana Appel Hort, Marcelo Farina
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/49decc64f14c41a2a0e79c6215755cf7
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