Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox

There had been an enduring discrepancy between theoretical and observed measurement of the DNA linking number (∆Lk) constrained by nucleosomes. Here the authors provide measurements of the ∆Lk constrained by individual nucleosomes in native chromatin that reconcile this discrepancy.

Guardado en:

Detalles Bibliográficos
Autores principales:	Joana Segura, Ricky S. Joshi, Ofelia Díaz-Ingelmo, Antonio Valdés, Silvia Dyson, Belén Martínez-García, Joaquim Roca
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/49e19b054dd7483da242053ec97e3ff6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:49e19b054dd7483da242053ec97e3ff6
record_format	dspace
spelling	oai:doaj.org-article:49e19b054dd7483da242053ec97e3ff62021-12-02T17:31:45ZIntracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox10.1038/s41467-018-06547-w2041-1723https://doaj.org/article/49e19b054dd7483da242053ec97e3ff62018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06547-whttps://doaj.org/toc/2041-1723There had been an enduring discrepancy between theoretical and observed measurement of the DNA linking number (∆Lk) constrained by nucleosomes. Here the authors provide measurements of the ∆Lk constrained by individual nucleosomes in native chromatin that reconcile this discrepancy.Joana SeguraRicky S. JoshiOfelia Díaz-IngelmoAntonio ValdésSilvia DysonBelén Martínez-GarcíaJoaquim RocaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joana Segura Ricky S. Joshi Ofelia Díaz-Ingelmo Antonio Valdés Silvia Dyson Belén Martínez-García Joaquim Roca Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
description	There had been an enduring discrepancy between theoretical and observed measurement of the DNA linking number (∆Lk) constrained by nucleosomes. Here the authors provide measurements of the ∆Lk constrained by individual nucleosomes in native chromatin that reconcile this discrepancy.
format	article
author	Joana Segura Ricky S. Joshi Ofelia Díaz-Ingelmo Antonio Valdés Silvia Dyson Belén Martínez-García Joaquim Roca
author_facet	Joana Segura Ricky S. Joshi Ofelia Díaz-Ingelmo Antonio Valdés Silvia Dyson Belén Martínez-García Joaquim Roca
author_sort	Joana Segura
title	Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
title_short	Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
title_full	Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
title_fullStr	Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
title_full_unstemmed	Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
title_sort	intracellular nucleosomes constrain a dna linking number difference of −1.26 that reconciles the lk paradox
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/49e19b054dd7483da242053ec97e3ff6
work_keys_str_mv	AT joanasegura intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT rickysjoshi intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT ofeliadiazingelmo intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT antoniovaldes intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT silviadyson intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT belenmartinezgarcia intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox AT joaquimroca intracellularnucleosomesconstrainadnalinkingnumberdifferenceof126thatreconcilesthelkparadox
_version_	1718380488044838912

Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox

Ejemplares similares