Influence of medications on taste and smell

Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medication...

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Autor principal:	Susan S. Schiffman
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2018
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/49e1cdb56144487cb9a4cdfc2d99a759
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spelling	oai:doaj.org-article:49e1cdb56144487cb9a4cdfc2d99a7592021-12-02T11:49:15ZInfluence of medications on taste and smell2095-881110.1016/j.wjorl.2018.02.005https://doaj.org/article/49e1cdb56144487cb9a4cdfc2d99a7592018-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881118300234https://doaj.org/toc/2095-8811Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medications. Some chemosensory complaints are due to the sensory properties of the drug itself such as aversive bitter and metallic tastes. However, most chemosensory side effects of drugs are due to alterations in the transduction pathways, biochemical targets, enzymes, and transporters by the offending medications. Studies of chemosensory perception in medicated older individuals have found that taste and smell loss is greatest for those consuming the largest number of prescription drugs. There are no standard treatments for drug-induced chemosensory disorders because each drug has unique biological effects. However, there are a few treatment options to ameliorate chemosensory alterations including addition of simulated flavors to food to compensate for losses and to override offending tastes and smells. Keywords: Taste disorders, Smell disorders, Chemosensory side effects of drugs, Drug–drug interactions, Bitter taste, Metallic tasteSusan S. SchiffmanKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 4, Iss 1, Pp 84-91 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Susan S. Schiffman Influence of medications on taste and smell
description	Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medications. Some chemosensory complaints are due to the sensory properties of the drug itself such as aversive bitter and metallic tastes. However, most chemosensory side effects of drugs are due to alterations in the transduction pathways, biochemical targets, enzymes, and transporters by the offending medications. Studies of chemosensory perception in medicated older individuals have found that taste and smell loss is greatest for those consuming the largest number of prescription drugs. There are no standard treatments for drug-induced chemosensory disorders because each drug has unique biological effects. However, there are a few treatment options to ameliorate chemosensory alterations including addition of simulated flavors to food to compensate for losses and to override offending tastes and smells. Keywords: Taste disorders, Smell disorders, Chemosensory side effects of drugs, Drug–drug interactions, Bitter taste, Metallic taste
format	article
author	Susan S. Schiffman
author_facet	Susan S. Schiffman
author_sort	Susan S. Schiffman
title	Influence of medications on taste and smell
title_short	Influence of medications on taste and smell
title_full	Influence of medications on taste and smell
title_fullStr	Influence of medications on taste and smell
title_full_unstemmed	Influence of medications on taste and smell
title_sort	influence of medications on taste and smell
publisher	KeAi Communications Co., Ltd.
publishDate	2018
url	https://doaj.org/article/49e1cdb56144487cb9a4cdfc2d99a759
work_keys_str_mv	AT susansschiffman influenceofmedicationsontasteandsmell
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Influence of medications on taste and smell

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