ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extract...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2014
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/49e755d5bcd64e0181521a12cbdc8d21 |
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| Sumario: | A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extracts a number of reactive oxygen species (O•-2, NO) revealed that they exhibit their ability to inactivate. With respect to Of-anion radical extracts show moderate and against NO - expressed antiradical activity (IC50 (DER-2) = 311.0 mkg/ml). We also revealed the presence of moderate Fe2+-chelating activity of the extracts studied. This effect is caused by apparently content of phenolic compounds, phenol carbonic acids, triterpene saponins and tannins. |
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