ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC

A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extract...

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Autores principales:	N. K. Tatarinova, I. V. Sviridov, A. A. Toropova, L. N. Shantanova, L. L. Garmayeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:	rhaponticum uniflorum (l.) dc dpph-радикал antioxidant activity dpph-radicals superoxide-radicals nitrogen oxide Science Q
Acceso en línea:	https://doaj.org/article/49e755d5bcd64e0181521a12cbdc8d21
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id	oai:doaj.org-article:49e755d5bcd64e0181521a12cbdc8d21
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spelling	oai:doaj.org-article:49e755d5bcd64e0181521a12cbdc8d212021-11-23T06:14:31ZANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC2541-94202587-9596https://doaj.org/article/49e755d5bcd64e0181521a12cbdc8d212014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1835https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extracts a number of reactive oxygen species (O•-2, NO) revealed that they exhibit their ability to inactivate. With respect to Of-anion radical extracts show moderate and against NO - expressed antiradical activity (IC50 (DER-2) = 311.0 mkg/ml). We also revealed the presence of moderate Fe2+-chelating activity of the extracts studied. This effect is caused by apparently content of phenolic compounds, phenol carbonic acids, triterpene saponins and tannins.N. K. TatarinovaI. V. SviridovA. A. ToropovaL. N. ShantanovaL. L. GarmayevaScientific Сentre for Family Health and Human Reproduction Problemsarticlerhaponticum uniflorum (l.) dcdpph-радикалrhaponticum uniflorum (l.) dcantioxidant activitydpph-radicalssuperoxide-radicalsnitrogen oxideScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 52-54 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	rhaponticum uniflorum (l.) dc dpph-радикал rhaponticum uniflorum (l.) dc antioxidant activity dpph-radicals superoxide-radicals nitrogen oxide Science Q
spellingShingle	rhaponticum uniflorum (l.) dc dpph-радикал rhaponticum uniflorum (l.) dc antioxidant activity dpph-radicals superoxide-radicals nitrogen oxide Science Q N. K. Tatarinova I. V. Sviridov A. A. Toropova L. N. Shantanova L. L. Garmayeva ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
description	A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extracts a number of reactive oxygen species (O•-2, NO) revealed that they exhibit their ability to inactivate. With respect to Of-anion radical extracts show moderate and against NO - expressed antiradical activity (IC50 (DER-2) = 311.0 mkg/ml). We also revealed the presence of moderate Fe2+-chelating activity of the extracts studied. This effect is caused by apparently content of phenolic compounds, phenol carbonic acids, triterpene saponins and tannins.
format	article
author	N. K. Tatarinova I. V. Sviridov A. A. Toropova L. N. Shantanova L. L. Garmayeva
author_facet	N. K. Tatarinova I. V. Sviridov A. A. Toropova L. N. Shantanova L. L. Garmayeva
author_sort	N. K. Tatarinova
title	ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
title_short	ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
title_full	ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
title_fullStr	ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
title_full_unstemmed	ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC
title_sort	antioxidant activity of the dry extract rhaponticum uniflorum (l.) dc
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/49e755d5bcd64e0181521a12cbdc8d21
work_keys_str_mv	AT nktatarinova antioxidantactivityofthedryextractrhaponticumuniflorumldc AT ivsviridov antioxidantactivityofthedryextractrhaponticumuniflorumldc AT aatoropova antioxidantactivityofthedryextractrhaponticumuniflorumldc AT lnshantanova antioxidantactivityofthedryextractrhaponticumuniflorumldc AT llgarmayeva antioxidantactivityofthedryextractrhaponticumuniflorumldc
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ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC

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