Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis

Andreas Rogalewski1, J&ouml;rg Kraus3, Martin Hasselblatt2, Christoffer Kraemer1, Wolf-R&uuml;diger Sch&auml;bitz11Department of Neurology; 2Institute of Neuropathology, University of Muenster, Germany, 3Paracelsus Private Medical University and Salzburger Landesklinken, Chri...

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Autores principales:	Andreas Rogalewski, J&ouml;rg Kraus, Martin Hasselblatt, Christoffer Kraemer, Wolf-R&uuml;diger Sch&auml;bitz
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2007
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/49e8d0aa11d34f7eb0e8c8ad12e74d86
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spelling	oai:doaj.org-article:49e8d0aa11d34f7eb0e8c8ad12e74d862021-12-02T02:28:28ZImprovement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis1176-63281178-2021https://doaj.org/article/49e8d0aa11d34f7eb0e8c8ad12e74d862007-01-01T00:00:00Zhttp://www.dovepress.com/improvement-of-advanced-postvaccinal-demyelinating-encephalitis-due-to-a980https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Andreas Rogalewski1, J&ouml;rg Kraus3, Martin Hasselblatt2, Christoffer Kraemer1, Wolf-R&uuml;diger Sch&auml;bitz11Department of Neurology; 2Institute of Neuropathology, University of Muenster, Germany, 3Paracelsus Private Medical University and Salzburger Landesklinken, Christian-Doppler-Klinik, Department of Neurology, Salzburg, AustriaAbstract: We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encephalitis and started treatment with high dose intravenous methylprednisolone, followed by peroral application in decreasing dosages for three weeks. A few days after the treatment with methylprednisolone had been finished, the patient&rsquo;s medical condition deteriorated again. Thus, we initiated plasma exchange at an advanced state of illness, which led to significant continuous improvement. The role of plasma exchange is discussed controversially, in particular the issue of timing. We report a case that shows improvement due to plasmapheresis several weeks after symptom onset.Keywords: ADEM, vaccination, encephalitis, plasmapheresis, demyelination, plasma exchange Andreas RogalewskiJ&ouml;rg KrausMartin HasselblattChristoffer KraemerWolf-R&uuml;diger Sch&auml;bitzDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2007, Iss Issue 6, Pp 987-991 (2007)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Andreas Rogalewski J&ouml;rg Kraus Martin Hasselblatt Christoffer Kraemer Wolf-R&uuml;diger Sch&auml;bitz Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
description	Andreas Rogalewski1, J&ouml;rg Kraus3, Martin Hasselblatt2, Christoffer Kraemer1, Wolf-R&uuml;diger Sch&auml;bitz11Department of Neurology; 2Institute of Neuropathology, University of Muenster, Germany, 3Paracelsus Private Medical University and Salzburger Landesklinken, Christian-Doppler-Klinik, Department of Neurology, Salzburg, AustriaAbstract: We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encephalitis and started treatment with high dose intravenous methylprednisolone, followed by peroral application in decreasing dosages for three weeks. A few days after the treatment with methylprednisolone had been finished, the patient&rsquo;s medical condition deteriorated again. Thus, we initiated plasma exchange at an advanced state of illness, which led to significant continuous improvement. The role of plasma exchange is discussed controversially, in particular the issue of timing. We report a case that shows improvement due to plasmapheresis several weeks after symptom onset.Keywords: ADEM, vaccination, encephalitis, plasmapheresis, demyelination, plasma exchange
format	article
author	Andreas Rogalewski J&ouml;rg Kraus Martin Hasselblatt Christoffer Kraemer Wolf-R&uuml;diger Sch&auml;bitz
author_facet	Andreas Rogalewski J&ouml;rg Kraus Martin Hasselblatt Christoffer Kraemer Wolf-R&uuml;diger Sch&auml;bitz
author_sort	Andreas Rogalewski
title	Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_short	Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_full	Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_fullStr	Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_full_unstemmed	Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_sort	improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
publisher	Dove Medical Press
publishDate	2007
url	https://doaj.org/article/49e8d0aa11d34f7eb0e8c8ad12e74d86
work_keys_str_mv	AT andreasrogalewski improvementofadvancedpostvaccinaldemyelinatingencephalitisduetoplasmapheresis AT jampoumlrgkraus improvementofadvancedpostvaccinaldemyelinatingencephalitisduetoplasmapheresis AT martinhasselblatt improvementofadvancedpostvaccinaldemyelinatingencephalitisduetoplasmapheresis AT christofferkraemer improvementofadvancedpostvaccinaldemyelinatingencephalitisduetoplasmapheresis AT wolframpuumldigerschampaumlbitz improvementofadvancedpostvaccinaldemyelinatingencephalitisduetoplasmapheresis
_version_	1718402464235913216

Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis

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