Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield

Abstract Water-dispersible up-converting nanoparticles (UCNPs) are known to be very effective in biomedical applications. Research groups have paid special attention to the synthesis of hydrophilic UCNPs with good physicochemical properties. Being aware of this, we decided to improve the ligand-free...

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Autores principales:	Natalia Jurga, Dominika Przybylska, Piotr Kamiński, Tomasz Grzyb
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/49ea6a1e64b841fe8a701ecf0b5260e4
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spelling	oai:doaj.org-article:49ea6a1e64b841fe8a701ecf0b5260e42021-12-02T18:48:23ZImprovement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield10.1038/s41598-021-98240-02045-2322https://doaj.org/article/49ea6a1e64b841fe8a701ecf0b5260e42021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98240-0https://doaj.org/toc/2045-2322Abstract Water-dispersible up-converting nanoparticles (UCNPs) are known to be very effective in biomedical applications. Research groups have paid special attention to the synthesis of hydrophilic UCNPs with good physicochemical properties. Being aware of this, we decided to improve the ligand-free modification method of OA-capped NaYF4:Yb3+,Er3+/NaYF4 UCNPs prepared by precipitation in high-boiling-point solvents as the thus-far reported methods do not provide satisfactory results. Different molarities of hydrochloric acid and various mixing times were selected to remove the organic ligand from the NPs’ surface and to discover the most promising modification approach. Highly water-stable colloids were obtained with a very high reaction yield of up to 96%. Moreover, the acid treatment did not affect the morphology and the size of the product. All of the crystals exhibited a bright up-conversion emission under 975-nm excitation, which confirmed the two-photon excitation and effective energy transfer between the used dopant ions. Thus, we could establish the most successful ligand-free modification procedure.Natalia JurgaDominika PrzybylskaPiotr KamińskiTomasz GrzybNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Natalia Jurga Dominika Przybylska Piotr Kamiński Tomasz Grzyb Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
description	Abstract Water-dispersible up-converting nanoparticles (UCNPs) are known to be very effective in biomedical applications. Research groups have paid special attention to the synthesis of hydrophilic UCNPs with good physicochemical properties. Being aware of this, we decided to improve the ligand-free modification method of OA-capped NaYF4:Yb3+,Er3+/NaYF4 UCNPs prepared by precipitation in high-boiling-point solvents as the thus-far reported methods do not provide satisfactory results. Different molarities of hydrochloric acid and various mixing times were selected to remove the organic ligand from the NPs’ surface and to discover the most promising modification approach. Highly water-stable colloids were obtained with a very high reaction yield of up to 96%. Moreover, the acid treatment did not affect the morphology and the size of the product. All of the crystals exhibited a bright up-conversion emission under 975-nm excitation, which confirmed the two-photon excitation and effective energy transfer between the used dopant ions. Thus, we could establish the most successful ligand-free modification procedure.
format	article
author	Natalia Jurga Dominika Przybylska Piotr Kamiński Tomasz Grzyb
author_facet	Natalia Jurga Dominika Przybylska Piotr Kamiński Tomasz Grzyb
author_sort	Natalia Jurga
title	Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
title_short	Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
title_full	Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
title_fullStr	Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
title_full_unstemmed	Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
title_sort	improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/49ea6a1e64b841fe8a701ecf0b5260e4
work_keys_str_mv	AT nataliajurga improvementofligandfreemodificationstrategytoobtainwaterstableupconvertingnanoparticleswithbrightemissionandhighreactionyield AT dominikaprzybylska improvementofligandfreemodificationstrategytoobtainwaterstableupconvertingnanoparticleswithbrightemissionandhighreactionyield AT piotrkaminski improvementofligandfreemodificationstrategytoobtainwaterstableupconvertingnanoparticleswithbrightemissionandhighreactionyield AT tomaszgrzyb improvementofligandfreemodificationstrategytoobtainwaterstableupconvertingnanoparticleswithbrightemissionandhighreactionyield
_version_	1718377619698745344

Improvement of ligand-free modification strategy to obtain water-stable up-converting nanoparticles with bright emission and high reaction yield

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