Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites

Abstract This study was aimed to evaluate the differences in the composition of gut microbiota, tryptophan metabolites and short-chain fatty acids in feces between volunteers who frequently ate chicken and who frequently ate pork. Twenty male chicken-eaters and 20 male pork-eaters of 18 and 30 years...

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Autores principales:	Jie Shi, Di Zhao, Fan Zhao, Chong Wang, Galia Zamaratskaia, Chunbao Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/49ed05e647d6439cb16325cc476763d7
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spelling	oai:doaj.org-article:49ed05e647d6439cb16325cc476763d72021-12-02T17:52:42ZChicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites10.1038/s41598-021-91429-32045-2322https://doaj.org/article/49ed05e647d6439cb16325cc476763d72021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91429-3https://doaj.org/toc/2045-2322Abstract This study was aimed to evaluate the differences in the composition of gut microbiota, tryptophan metabolites and short-chain fatty acids in feces between volunteers who frequently ate chicken and who frequently ate pork. Twenty male chicken-eaters and 20 male pork-eaters of 18 and 30 years old were recruited to collect feces samples for analyses of gut microbiota composition, short-chain fatty acids and tryptophan metabolites. Chicken-eaters had more diverse gut microbiota and higher abundance of Prevotella 9, Dialister, Faecalibacterium, Megamonas, and Prevotella 2. However, pork-eaters had higher relative abundance of Bacteroides, Faecalibacterium, Roseburia, Dialister, and Ruminococcus 2. In addition, chicken-eaters had high contents of skatole and indole in feces than pork-eaters, as well as higher contents of total short chain fatty acids, in particular for acetic acid, propionic acid, and branched chain fatty acids. The Spearman’s correlation analysis revealed that the abundance of Prevotella 2 and Prevotella 9 was positively correlated with levels of fecal skatole, indole and short-chain fatty acids. Thus, intake of chicken diet may increase the risk of skatole- and indole-induced diseases by altering gut microbiota.Jie ShiDi ZhaoFan ZhaoChong WangGalia ZamaratskaiaChunbao LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jie Shi Di Zhao Fan Zhao Chong Wang Galia Zamaratskaia Chunbao Li Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
description	Abstract This study was aimed to evaluate the differences in the composition of gut microbiota, tryptophan metabolites and short-chain fatty acids in feces between volunteers who frequently ate chicken and who frequently ate pork. Twenty male chicken-eaters and 20 male pork-eaters of 18 and 30 years old were recruited to collect feces samples for analyses of gut microbiota composition, short-chain fatty acids and tryptophan metabolites. Chicken-eaters had more diverse gut microbiota and higher abundance of Prevotella 9, Dialister, Faecalibacterium, Megamonas, and Prevotella 2. However, pork-eaters had higher relative abundance of Bacteroides, Faecalibacterium, Roseburia, Dialister, and Ruminococcus 2. In addition, chicken-eaters had high contents of skatole and indole in feces than pork-eaters, as well as higher contents of total short chain fatty acids, in particular for acetic acid, propionic acid, and branched chain fatty acids. The Spearman’s correlation analysis revealed that the abundance of Prevotella 2 and Prevotella 9 was positively correlated with levels of fecal skatole, indole and short-chain fatty acids. Thus, intake of chicken diet may increase the risk of skatole- and indole-induced diseases by altering gut microbiota.
format	article
author	Jie Shi Di Zhao Fan Zhao Chong Wang Galia Zamaratskaia Chunbao Li
author_facet	Jie Shi Di Zhao Fan Zhao Chong Wang Galia Zamaratskaia Chunbao Li
author_sort	Jie Shi
title	Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
title_short	Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
title_full	Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
title_fullStr	Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
title_full_unstemmed	Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
title_sort	chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/49ed05e647d6439cb16325cc476763d7
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Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites

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