IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT

Abstract. We have examined the effect of betaleukin on the immune parameters in breast cancer (BC) patients treated with cytostatic drug and surgery. Intravenous application of betaleukin for 5 days just before adjuvant chemotherapy have been shown to prevent both the decrease of blood immune cell c...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	M. Staheeva, E. Slonymskaya, N. Babyshkina, N. Cherdyntseva, A. Simbirtsev, A. Kladiev
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	betaleukin immunity breast cancer Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/49ef38cfa4404dca9139db3856b25b40
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:49ef38cfa4404dca9139db3856b25b40
record_format	dspace
spelling	oai:doaj.org-article:49ef38cfa4404dca9139db3856b25b402021-11-18T08:03:41ZIMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT1563-06252313-741X10.15789/1563-0625-2005-1-63-72https://doaj.org/article/49ef38cfa4404dca9139db3856b25b402014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/427https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have examined the effect of betaleukin on the immune parameters in breast cancer (BC) patients treated with cytostatic drug and surgery. Intravenous application of betaleukin for 5 days just before adjuvant chemotherapy have been shown to prevent both the decrease of blood immune cell count and the damage of their functional activity in BC patients with lymph node involvement N0–1. BC patients with wide spreading lymph node metastases N2 showed the protection of blood neutrophil activity but not lymphocyte subset count following betaleukin administration and chemotherapy. Positive effect of betaleukin was found to depend upon the adaptive state of patients. Betaleukin in turn appeared to display the adaptogenic activity. (Med. Immunol., 2005, vol.7, № 1, pp 63572)M. StaheevaE. SlonymskayaN. BabyshkinaN. CherdyntsevaA. SimbirtsevA. KladievSPb RAACIarticlebetaleukinimmunitybreast cancerImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 1, Pp 63-72 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	betaleukin immunity breast cancer Immunologic diseases. Allergy RC581-607
spellingShingle	betaleukin immunity breast cancer Immunologic diseases. Allergy RC581-607 M. Staheeva E. Slonymskaya N. Babyshkina N. Cherdyntseva A. Simbirtsev A. Kladiev IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
description	Abstract. We have examined the effect of betaleukin on the immune parameters in breast cancer (BC) patients treated with cytostatic drug and surgery. Intravenous application of betaleukin for 5 days just before adjuvant chemotherapy have been shown to prevent both the decrease of blood immune cell count and the damage of their functional activity in BC patients with lymph node involvement N0–1. BC patients with wide spreading lymph node metastases N2 showed the protection of blood neutrophil activity but not lymphocyte subset count following betaleukin administration and chemotherapy. Positive effect of betaleukin was found to depend upon the adaptive state of patients. Betaleukin in turn appeared to display the adaptogenic activity. (Med. Immunol., 2005, vol.7, № 1, pp 63572)
format	article
author	M. Staheeva E. Slonymskaya N. Babyshkina N. Cherdyntseva A. Simbirtsev A. Kladiev
author_facet	M. Staheeva E. Slonymskaya N. Babyshkina N. Cherdyntseva A. Simbirtsev A. Kladiev
author_sort	M. Staheeva
title	IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
title_short	IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
title_full	IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
title_fullStr	IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
title_full_unstemmed	IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT
title_sort	immunological parameters in breast cancer patients under betaleukin adjuvant treatment
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/49ef38cfa4404dca9139db3856b25b40
work_keys_str_mv	AT mstaheeva immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment AT eslonymskaya immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment AT nbabyshkina immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment AT ncherdyntseva immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment AT asimbirtsev immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment AT akladiev immunologicalparametersinbreastcancerpatientsunderbetaleukinadjuvanttreatment
_version_	1718422474554605568

IMMUNOLOGICAL PARAMETERS IN BREAST CANCER PATIENTS UNDER BETALEUKIN ADJUVANT TREATMENT

Ejemplares similares