SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition

ABSTRACT Macrophages are susceptible to human immunodeficiency virus type 1 (HIV-1) infection despite abundant expression of antiviral proteins. Perhaps the most important antiviral protein is the restriction factor sterile alpha motif domain and histidine/aspartic acid domain-containing protein 1 (...

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Bibliographic Details
Main Authors: Matthew A. Szaniawski, Adam M. Spivak, James E. Cox, Jonathan L. Catrow, Timothy Hanley, Elizabeth S. C. P. Williams, Michel J. Tremblay, Alberto Bosque, Vicente Planelles
Format: article
Language:EN
Published: American Society for Microbiology 2018
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Online Access:https://doaj.org/article/4a024d48ae774db5890199c452df8a52
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