Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis

Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and p...

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Autores principales: Cervantes LJ, Mah FS
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Lenguaje:EN
Publicado: Dove Medical Press 2011
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Acceso en línea:https://doaj.org/article/4a065ecae35f4ce190c02a2c3d4007c7
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spelling oai:doaj.org-article:4a065ecae35f4ce190c02a2c3d4007c72021-12-02T01:36:56ZClinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis1177-54671177-5483https://doaj.org/article/4a065ecae35f4ce190c02a2c3d4007c72011-04-01T00:00:00Zhttp://www.dovepress.com/clinical-use-of-gatifloxacin-ophthalmic-solution-for-treatment-of-bact-a7119https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.Keywords: gatifloxacin, Zymar®, Zymaxid®, bacterial conjunctivitis Cervantes LJMah FSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 495-502 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Cervantes LJ
Mah FS
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
description Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.Keywords: gatifloxacin, Zymar®, Zymaxid®, bacterial conjunctivitis
format article
author Cervantes LJ
Mah FS
author_facet Cervantes LJ
Mah FS
author_sort Cervantes LJ
title Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
title_short Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
title_full Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
title_fullStr Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
title_full_unstemmed Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
title_sort clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/4a065ecae35f4ce190c02a2c3d4007c7
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