Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and p...
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Dove Medical Press
2011
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oai:doaj.org-article:4a065ecae35f4ce190c02a2c3d4007c72021-12-02T01:36:56ZClinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis1177-54671177-5483https://doaj.org/article/4a065ecae35f4ce190c02a2c3d4007c72011-04-01T00:00:00Zhttp://www.dovepress.com/clinical-use-of-gatifloxacin-ophthalmic-solution-for-treatment-of-bact-a7119https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.Keywords: gatifloxacin, Zymar®, Zymaxid®, bacterial conjunctivitis Cervantes LJMah FSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 495-502 (2011) |
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Ophthalmology RE1-994 Cervantes LJ Mah FS Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
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Lorenzo J Cervantes, Francis S MahDepartment of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USAAbstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.Keywords: gatifloxacin, Zymar®, Zymaxid®, bacterial conjunctivitis |
format |
article |
author |
Cervantes LJ Mah FS |
author_facet |
Cervantes LJ Mah FS |
author_sort |
Cervantes LJ |
title |
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
title_short |
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
title_full |
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
title_fullStr |
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
title_full_unstemmed |
Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
title_sort |
clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis |
publisher |
Dove Medical Press |
publishDate |
2011 |
url |
https://doaj.org/article/4a065ecae35f4ce190c02a2c3d4007c7 |
work_keys_str_mv |
AT cervanteslj clinicaluseofgatifloxacinophthalmicsolutionfortreatmentofbacterialconjunctivitis AT mahfs clinicaluseofgatifloxacinophthalmicsolutionfortreatmentofbacterialconjunctivitis |
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