SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection

SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection

Why children are generally less susceptible than adults to COVID-19 is unclear and has not extensively been examined longitudinally. Here the authors compare antibodies, cytokines and immune cell responses in adults and children over 6 months post-infection showing, among other things, a reduced CD4...

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Autores principales: Carolyn A. Cohen, Athena P. Y. Li, Asmaa Hachim, David S. C. Hui, Mike Y. W. Kwan, Owen T. Y. Tsang, Susan S. Chiu, Wai Hung Chan, Yat Sun Yau, Niloufar Kavian, Fionn N. L. Ma, Eric H. Y. Lau, Samuel M. S. Cheng, Leo L. M. Poon, Malik Peiris, Sophie A. Valkenburg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/4a06b354eca4474d953f5855491515f4
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Sumario:Why children are generally less susceptible than adults to COVID-19 is unclear and has not extensively been examined longitudinally. Here the authors compare antibodies, cytokines and immune cell responses in adults and children over 6 months post-infection showing, among other things, a reduced CD4+ and CD8+ T cell response in children.

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