Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)

Adolescents with idiopathic scoliosis (AIS) often receive conservative treatments aiming to prevent progression of the spinal deformity during puberty. This study aimed to explore patient adherence and secondary outcomes during the first 6 months in an ongoing randomised controlled trial of three tr...

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Autores principales:	Marlene Dufvenberg, Elias Diarbakerli, Anastasios Charalampidis, Birgitta Öberg, Hans Tropp, Anna Aspberg Ahl, Hans Möller, Paul Gerdhem, Allan Abbott
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	idiopathic scoliosis bracing physiotherapeutic scoliosis-specific exercise physical activity adherence spinal appearance Medicine R
Acceso en línea:	https://doaj.org/article/4a15c8e7d9af44668cc446440320ccfd
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spelling	oai:doaj.org-article:4a15c8e7d9af44668cc446440320ccfd2021-11-11T17:36:00ZSix-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)10.3390/jcm102149672077-0383https://doaj.org/article/4a15c8e7d9af44668cc446440320ccfd2021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/4967https://doaj.org/toc/2077-0383Adolescents with idiopathic scoliosis (AIS) often receive conservative treatments aiming to prevent progression of the spinal deformity during puberty. This study aimed to explore patient adherence and secondary outcomes during the first 6 months in an ongoing randomised controlled trial of three treatment interventions. Interventions consisted of physical activity combined with either hypercorrective Boston brace night shift (NB), scoliosis-specific exercise (SSE), or physical activity alone (PA). Measures at baseline and 6 months included angle of trunk rotation (ATR), Cobb angle, International Physical Activity Questionnaire short form (IPAQ-SF), pictorial Spinal Appearance Questionnaire (pSAQ), Scoliosis Research Society (SRS-22r), EuroQol 5-Dimensions Youth (EQ-5D-Y) and Visual Analogue Scale (EQ-VAS). Patient adherence, motivation, and capability in performing the intervention were reported at 6 months. The study included 135 patients (111 females) with AIS and >1-year estimated remaining growth, mean age 12.7 (1.4) years, and mean Cobb angle 31 (±5.3). At 6 months, the proportion of patients in the groups reporting high to very high adherence ranged between 72 and 95%, while motivation ranged between 65 and 92%, with the highest proportion seen in the NB group (<i>p</i> = 0.014, <i>p</i>= 0.002). IPAQ-SF displayed significant between group main effects regarding moderate activity (F = 5.7; <i>p</i> = 0.004; η<sub>p<sup>2</sup></sub> = 0.10), with a medium-sized increase favouring the SSE group compared to NB. Walking showed significant between group main effects, as did metabolic equivalent (MET-min/week), with medium (F = 6.8, <i>p</i> = 0.002; η<sub>p<sup>2</sup></sub> = 0.11, and large (F = 8.3, <i>p</i> = < 0.001, η<sub>p<sup>2</sup></sub> = 0.14) increases, respectively, for the SSE and PA groups compared to NB. From baseline to 6 months, ATR showed significant between group medium-sized main effects (F = 1.2, <i>p</i> = 0.019, η<sub>p<sup>2</sup></sub> = 0.007) favouring the NB group compared to PA, but not reaching a clinically relevant level. In conclusion, patients reported high adherence and motivation to treatment, especially in the NB group. Patients in the SSE and PA groups increased their physical activity levels without other clinically relevant differences between groups in other clinical measures or patient-reported outcomes. The results suggest that the prescribed treatments are viable first-step options during the first 6 months.Marlene DufvenbergElias DiarbakerliAnastasios CharalampidisBirgitta ÖbergHans TroppAnna Aspberg AhlHans MöllerPaul GerdhemAllan AbbottMDPI AGarticleidiopathic scoliosisbracingphysiotherapeutic scoliosis-specific exercisephysical activityadherencespinal appearanceMedicineRENJournal of Clinical Medicine, Vol 10, Iss 4967, p 4967 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	idiopathic scoliosis bracing physiotherapeutic scoliosis-specific exercise physical activity adherence spinal appearance Medicine R
spellingShingle	idiopathic scoliosis bracing physiotherapeutic scoliosis-specific exercise physical activity adherence spinal appearance Medicine R Marlene Dufvenberg Elias Diarbakerli Anastasios Charalampidis Birgitta Öberg Hans Tropp Anna Aspberg Ahl Hans Möller Paul Gerdhem Allan Abbott Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
description	Adolescents with idiopathic scoliosis (AIS) often receive conservative treatments aiming to prevent progression of the spinal deformity during puberty. This study aimed to explore patient adherence and secondary outcomes during the first 6 months in an ongoing randomised controlled trial of three treatment interventions. Interventions consisted of physical activity combined with either hypercorrective Boston brace night shift (NB), scoliosis-specific exercise (SSE), or physical activity alone (PA). Measures at baseline and 6 months included angle of trunk rotation (ATR), Cobb angle, International Physical Activity Questionnaire short form (IPAQ-SF), pictorial Spinal Appearance Questionnaire (pSAQ), Scoliosis Research Society (SRS-22r), EuroQol 5-Dimensions Youth (EQ-5D-Y) and Visual Analogue Scale (EQ-VAS). Patient adherence, motivation, and capability in performing the intervention were reported at 6 months. The study included 135 patients (111 females) with AIS and >1-year estimated remaining growth, mean age 12.7 (1.4) years, and mean Cobb angle 31 (±5.3). At 6 months, the proportion of patients in the groups reporting high to very high adherence ranged between 72 and 95%, while motivation ranged between 65 and 92%, with the highest proportion seen in the NB group (<i>p</i> = 0.014, <i>p</i>= 0.002). IPAQ-SF displayed significant between group main effects regarding moderate activity (F = 5.7; <i>p</i> = 0.004; η<sub>p<sup>2</sup></sub> = 0.10), with a medium-sized increase favouring the SSE group compared to NB. Walking showed significant between group main effects, as did metabolic equivalent (MET-min/week), with medium (F = 6.8, <i>p</i> = 0.002; η<sub>p<sup>2</sup></sub> = 0.11, and large (F = 8.3, <i>p</i> = < 0.001, η<sub>p<sup>2</sup></sub> = 0.14) increases, respectively, for the SSE and PA groups compared to NB. From baseline to 6 months, ATR showed significant between group medium-sized main effects (F = 1.2, <i>p</i> = 0.019, η<sub>p<sup>2</sup></sub> = 0.007) favouring the NB group compared to PA, but not reaching a clinically relevant level. In conclusion, patients reported high adherence and motivation to treatment, especially in the NB group. Patients in the SSE and PA groups increased their physical activity levels without other clinically relevant differences between groups in other clinical measures or patient-reported outcomes. The results suggest that the prescribed treatments are viable first-step options during the first 6 months.
format	article
author	Marlene Dufvenberg Elias Diarbakerli Anastasios Charalampidis Birgitta Öberg Hans Tropp Anna Aspberg Ahl Hans Möller Paul Gerdhem Allan Abbott
author_facet	Marlene Dufvenberg Elias Diarbakerli Anastasios Charalampidis Birgitta Öberg Hans Tropp Anna Aspberg Ahl Hans Möller Paul Gerdhem Allan Abbott
author_sort	Marlene Dufvenberg
title	Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
title_short	Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
title_full	Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
title_fullStr	Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
title_full_unstemmed	Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)
title_sort	six-month results on treatment adherence, physical activity, spinal appearance, spinal deformity, and quality of life in an ongoing randomised trial on conservative treatment for adolescent idiopathic scoliosis (contrais)
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/4a15c8e7d9af44668cc446440320ccfd
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Six-Month Results on Treatment Adherence, Physical Activity, Spinal Appearance, Spinal Deformity, and Quality of Life in an Ongoing Randomised Trial on Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS)

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