Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury

Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the in...

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Autores principales: Ramezanikhah Hajar, Farrokhi Ahmad, Nejatbakhsh Reza, Shokri Saeed, Zendedel Adib, Abdanipour Alireza
Formato: article
Lenguaje:EN
Publicado: Sciendo 2020
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Acceso en línea:https://doaj.org/article/4a228655c8ff4ef498aee69ff8edac4c
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Sumario:Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the inflammasome components following SCI in testis over a defined time periods.