Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury

Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the in...

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Autores principales: Ramezanikhah Hajar, Farrokhi Ahmad, Nejatbakhsh Reza, Shokri Saeed, Zendedel Adib, Abdanipour Alireza
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Lenguaje:EN
Publicado: Sciendo 2020
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Acceso en línea:https://doaj.org/article/4a228655c8ff4ef498aee69ff8edac4c
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spelling oai:doaj.org-article:4a228655c8ff4ef498aee69ff8edac4c2021-12-02T16:41:14ZInvolvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury1336-032910.2478/enr-2020-0012https://doaj.org/article/4a228655c8ff4ef498aee69ff8edac4c2020-04-01T00:00:00Zhttps://doi.org/10.2478/enr-2020-0012https://doaj.org/toc/1336-0329Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the inflammasome components following SCI in testis over a defined time periods.Ramezanikhah HajarFarrokhi AhmadNejatbakhsh RezaShokri SaeedZendedel AdibAbdanipour AlirezaSciendoarticleinflammasomesspinal cord injurytestisDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 54, Iss 2, Pp 96-108 (2020)
institution DOAJ
collection DOAJ
language EN
topic inflammasomes
spinal cord injury
testis
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle inflammasomes
spinal cord injury
testis
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Ramezanikhah Hajar
Farrokhi Ahmad
Nejatbakhsh Reza
Shokri Saeed
Zendedel Adib
Abdanipour Alireza
Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
description Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the inflammasome components following SCI in testis over a defined time periods.
format article
author Ramezanikhah Hajar
Farrokhi Ahmad
Nejatbakhsh Reza
Shokri Saeed
Zendedel Adib
Abdanipour Alireza
author_facet Ramezanikhah Hajar
Farrokhi Ahmad
Nejatbakhsh Reza
Shokri Saeed
Zendedel Adib
Abdanipour Alireza
author_sort Ramezanikhah Hajar
title Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
title_short Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
title_full Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
title_fullStr Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
title_full_unstemmed Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
title_sort involvement of asc and nlrp3 inflammasomes in the testes following spinal cord injury
publisher Sciendo
publishDate 2020
url https://doaj.org/article/4a228655c8ff4ef498aee69ff8edac4c
work_keys_str_mv AT ramezanikhahhajar involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
AT farrokhiahmad involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
AT nejatbakhshreza involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
AT shokrisaeed involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
AT zendedeladib involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
AT abdanipouralireza involvementofascandnlrp3inflammasomesinthetestesfollowingspinalcordinjury
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