SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS

Objective: To determine the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in diabetic patients with end-stage renal failure (ESRF) undergoing hemodialysis. Study Design: Cross-sectional study. Place and Duration of Study:...

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Autores principales:	Bushra Jabbar, Qamar Ul Islam, Muhammad Kashif Hanif, Ubaidullah Yasin, Omer Farooq, Saman Fatima
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	endstage renal failure hemodialysis macular thickness retinal nerve fibre layer thickness Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4a2430c5013145328c75df5ffc9bcd50
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spelling	oai:doaj.org-article:4a2430c5013145328c75df5ffc9bcd502021-12-02T14:54:22ZSHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESSdoi.org/10.51253/pafmj.v70i6.40400030-96482411-8842https://doaj.org/article/4a2430c5013145328c75df5ffc9bcd502020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/4040https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in diabetic patients with end-stage renal failure (ESRF) undergoing hemodialysis. Study Design: Cross-sectional study. Place and Duration of Study: Pakistan Naval Ship, Shifa Karachi, from Jan 2019 to Jul 2019 Methodology: Fifty four patients presenting to nephrology department who met the inclusion criteria were included in the study. Macular and retinal nerve fibre layer thicknesses were compared pre and post 30 minutes of hemodialysis and their correlation (r=-0.89) with age, duration of hemodialysis and gender was examined. Pre hemodialysis temporal, inferior, average retinal nerve fibre layer thicknesses were observed thinner than Post hemodialysis. Results: Pre-hemodialysis macular thicknesses were thinner than post hemodialysis. Thinning of Macular and RNFL showed a negative relationship with age and duration of hemodialysis (r=-0.89 & -0.76). Temporal, superior quadrants and average retinal nerve fiber layer thickness values were found statistically different in pre and post 30 minutes hemodialysis examination (p-value = 0.002, 0.001 & 0.0021) while, nasal and inferior quadrants were found statistically insignificant. Whereas in macula, temporal and superior quadrants were found statistically significant (p-value=0.005 & 0.002) and nasal, Inferior and average thickness were found statistically insignificant (p-value = 0.0641, 0.0594 & 0.083). Conclusion: Macular and retinal nerve fiber layer thicknesses of patients receiving hemodialysis were less than the normal population. Age has no effect on these thinning. The duration of hemodialysis effects more than gender. Hemodialysis session causes a consistent.............Bushra JabbarQamar Ul IslamMuhammad Kashif HanifUbaidullah YasinOmer FarooqSaman FatimaArmy Medical College Rawalpindiarticleendstage renal failurehemodialysismacular thicknessretinal nerve fibre layer thicknessMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 6, Pp 1804-1809 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	endstage renal failure hemodialysis macular thickness retinal nerve fibre layer thickness Medicine R Medicine (General) R5-920
spellingShingle	endstage renal failure hemodialysis macular thickness retinal nerve fibre layer thickness Medicine R Medicine (General) R5-920 Bushra Jabbar Qamar Ul Islam Muhammad Kashif Hanif Ubaidullah Yasin Omer Farooq Saman Fatima SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
description	Objective: To determine the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in diabetic patients with end-stage renal failure (ESRF) undergoing hemodialysis. Study Design: Cross-sectional study. Place and Duration of Study: Pakistan Naval Ship, Shifa Karachi, from Jan 2019 to Jul 2019 Methodology: Fifty four patients presenting to nephrology department who met the inclusion criteria were included in the study. Macular and retinal nerve fibre layer thicknesses were compared pre and post 30 minutes of hemodialysis and their correlation (r=-0.89) with age, duration of hemodialysis and gender was examined. Pre hemodialysis temporal, inferior, average retinal nerve fibre layer thicknesses were observed thinner than Post hemodialysis. Results: Pre-hemodialysis macular thicknesses were thinner than post hemodialysis. Thinning of Macular and RNFL showed a negative relationship with age and duration of hemodialysis (r=-0.89 & -0.76). Temporal, superior quadrants and average retinal nerve fiber layer thickness values were found statistically different in pre and post 30 minutes hemodialysis examination (p-value = 0.002, 0.001 & 0.0021) while, nasal and inferior quadrants were found statistically insignificant. Whereas in macula, temporal and superior quadrants were found statistically significant (p-value=0.005 & 0.002) and nasal, Inferior and average thickness were found statistically insignificant (p-value = 0.0641, 0.0594 & 0.083). Conclusion: Macular and retinal nerve fiber layer thicknesses of patients receiving hemodialysis were less than the normal population. Age has no effect on these thinning. The duration of hemodialysis effects more than gender. Hemodialysis session causes a consistent.............
format	article
author	Bushra Jabbar Qamar Ul Islam Muhammad Kashif Hanif Ubaidullah Yasin Omer Farooq Saman Fatima
author_facet	Bushra Jabbar Qamar Ul Islam Muhammad Kashif Hanif Ubaidullah Yasin Omer Farooq Saman Fatima
author_sort	Bushra Jabbar
title	SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
title_short	SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
title_full	SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
title_fullStr	SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
title_full_unstemmed	SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS
title_sort	short term effect of hemodialysis on peripapillary retinal nerve fiber layer and macular thickness
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/4a2430c5013145328c75df5ffc9bcd50
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SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS

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