Structural and Regulatory Changes in PBP4 Trigger Decreased β-Lactam Susceptibility in <named-content content-type="genus-species">Enterococcus faecalis</named-content>

Structural and Regulatory Changes in PBP4 Trigger Decreased β-Lactam Susceptibility in <named-content content-type="genus-species">Enterococcus faecalis</named-content>

ABSTRACT Enterococcus faecalis strains resistant to penicillin and ampicillin are rare and have been associated with increases in quantities of low-affinity penicillin-binding protein 4 (PBP4) or with amino acid substitutions in PBP4. We report an E. faecalis strain (LS4828) isolated from a prosthet...

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Autores principales: Louis B. Rice, Charlene Desbonnet, Amelia Tait-Kamradt, Monica Garcia-Solache, John Lonks, Thomas M. Moon, Éverton D. D’Andréa, Rebecca Page, Wolfgang Peti
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
antibiotic resistance
Enterococcus
penicillin-binding proteins
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/4a29d6e56744499296c4f18b97663da3
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