Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy

Barbara Delas, Lorena Almud&iacute;, Anabel Carreras, Mouafk AsaadOphthalmology Service, Hospital de Terrassa, Barcelona, SpainObjective: To report a good clinical outcome in a patient with bilateral choroidal neovascularization (CNV) associated with optic nerve head drusen (ONHD) treated wi...

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Autores principales:	Carreras A, Almud&iacute; L, Delas B, Asaad M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/4a2a1df972e04b639b936a8c6938b5ff
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spelling	oai:doaj.org-article:4a2a1df972e04b639b936a8c6938b5ff2021-12-02T01:41:11ZBilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy1177-54671177-5483https://doaj.org/article/4a2a1df972e04b639b936a8c6938b5ff2012-02-01T00:00:00Zhttp://www.dovepress.com/bilateral-choroidal-neovascularization-associated-with-optic-nerve-hea-a9251https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Barbara Delas, Lorena Almud&iacute;, Anabel Carreras, Mouafk AsaadOphthalmology Service, Hospital de Terrassa, Barcelona, SpainObjective: To report a good clinical outcome in a patient with bilateral choroidal neovascularization (CNV) associated with optic nerve head drusen (ONHD) treated with intravitreal ranibizumab injection.Methods: A 12-year-old girl was referred for loss of right eye vision detected in a routine check-up. Best-corrected visual acuity (BCVA) was hand movements in the right eye and 0.9 in the left eye. Funduscopy revealed the presence of superficial and buried bilateral ONHD, which was confirmed by ultrasonography and computed tomography, and the study was completed with perimetry. The presence of bilateral CNV, active in the right eye, was observed and subsequently confirmed using fluorescein angiography and optical coherence tomography.Results: Treatment with two consecutive injections of intravitreal ranibizumab resulted in inactivation of the neovascular membrane with subretinal fluid reabsorption and improved right eye BCVA. After 12 months&rsquo; follow-up, this was 20/60 and stable.Conclusion: Although there are no published studies of safety in children, antiangiogenic therapy for CNV secondary to ONHD may be useful and safe. A search of the literature produced only one previously reported case of ONHD-associated CNV treated with antivascular endothelial growth factor alone.Keywords: optic nerve head drusen, anti-vegf, children, neovascularisationCarreras AAlmud&iacute; LDelas BAsaad MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 225-230 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Carreras A Almud&iacute; L Delas B Asaad M Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
description	Barbara Delas, Lorena Almud&iacute;, Anabel Carreras, Mouafk AsaadOphthalmology Service, Hospital de Terrassa, Barcelona, SpainObjective: To report a good clinical outcome in a patient with bilateral choroidal neovascularization (CNV) associated with optic nerve head drusen (ONHD) treated with intravitreal ranibizumab injection.Methods: A 12-year-old girl was referred for loss of right eye vision detected in a routine check-up. Best-corrected visual acuity (BCVA) was hand movements in the right eye and 0.9 in the left eye. Funduscopy revealed the presence of superficial and buried bilateral ONHD, which was confirmed by ultrasonography and computed tomography, and the study was completed with perimetry. The presence of bilateral CNV, active in the right eye, was observed and subsequently confirmed using fluorescein angiography and optical coherence tomography.Results: Treatment with two consecutive injections of intravitreal ranibizumab resulted in inactivation of the neovascular membrane with subretinal fluid reabsorption and improved right eye BCVA. After 12 months&rsquo; follow-up, this was 20/60 and stable.Conclusion: Although there are no published studies of safety in children, antiangiogenic therapy for CNV secondary to ONHD may be useful and safe. A search of the literature produced only one previously reported case of ONHD-associated CNV treated with antivascular endothelial growth factor alone.Keywords: optic nerve head drusen, anti-vegf, children, neovascularisation
format	article
author	Carreras A Almud&iacute; L Delas B Asaad M
author_facet	Carreras A Almud&iacute; L Delas B Asaad M
author_sort	Carreras A
title	Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
title_short	Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
title_full	Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
title_fullStr	Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
title_full_unstemmed	Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
title_sort	bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/4a2a1df972e04b639b936a8c6938b5ff
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Bilateral choroidal neovascularization associated with optic nerve head drusen treated by antivascular endothelial growth factor therapy

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