Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study

Aim: The aim of this study was to find out the association of adiponectin and resistin levels in gingival crevicular fluid (GCF) with the clinical parameters before and after scaling and root planing in periodontitis patients. Methods: A total of 50 patients were recruited from the Outpatient Depart...

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Autores principales:	P Fairlin, S A Jacob Raja, Johnson Raja James, Tamil Selvan Kumar, Ravi Shankar, S Divya
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	adiponectin chronic periodontitis resistin Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/4a2fb6588c0e4d8281fc3b484a7ddac1
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spelling	oai:doaj.org-article:4a2fb6588c0e4d8281fc3b484a7ddac12021-11-19T12:15:52ZEvaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study0975-740610.4103/jpbs.jpbs_318_21https://doaj.org/article/4a2fb6588c0e4d8281fc3b484a7ddac12021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1178;epage=1183;aulast=Fairlinhttps://doaj.org/toc/0975-7406Aim: The aim of this study was to find out the association of adiponectin and resistin levels in gingival crevicular fluid (GCF) with the clinical parameters before and after scaling and root planing in periodontitis patients. Methods: A total of 50 patients were recruited from the Outpatient Department of Periodontics, JKK Nattraja Dental College and Hospital, Komarapalayam, Tamil Nadu, India. The protocol was reviewed and approved by the institutional ethical board. Informed consent was obtained from the patients and the study-related procedures were explained. Patients were divided into two groups. Group I (25 patients) consisted of healthy patients. Group II (25 patients) consisted of periodontitis patients. The periodontitis patients after treatment were considered as Group III. GCF samples were collected before treatment and 21 days after treatment. The levels of adiponectin and resistin were evaluated using Immunotag™ Human RETN enzyme-linked immunosorbent assay (ELISA) kit (ITEH0269) and Immunotag™ Human ADP (adiponectin) ELISA kit (ITEH2593). The levels were correlated with the clinical parameters. Results: There were an increase in the mean adiponectin level and a decrease in the mean resistin level at the end of periodontal therapy. Conclusions: Adiponectin which is an anti-inflammatory component was found to increase after periodontal therapy, and resistin which is an inflammatory component has been decreased after periodontal therapy.P FairlinS A Jacob RajaJohnson Raja JamesTamil Selvan KumarRavi ShankarS DivyaWolters Kluwer Medknow Publicationsarticleadiponectinchronic periodontitisresistinPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1178-1183 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	adiponectin chronic periodontitis resistin Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
spellingShingle	adiponectin chronic periodontitis resistin Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 P Fairlin S A Jacob Raja Johnson Raja James Tamil Selvan Kumar Ravi Shankar S Divya Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
description	Aim: The aim of this study was to find out the association of adiponectin and resistin levels in gingival crevicular fluid (GCF) with the clinical parameters before and after scaling and root planing in periodontitis patients. Methods: A total of 50 patients were recruited from the Outpatient Department of Periodontics, JKK Nattraja Dental College and Hospital, Komarapalayam, Tamil Nadu, India. The protocol was reviewed and approved by the institutional ethical board. Informed consent was obtained from the patients and the study-related procedures were explained. Patients were divided into two groups. Group I (25 patients) consisted of healthy patients. Group II (25 patients) consisted of periodontitis patients. The periodontitis patients after treatment were considered as Group III. GCF samples were collected before treatment and 21 days after treatment. The levels of adiponectin and resistin were evaluated using Immunotag™ Human RETN enzyme-linked immunosorbent assay (ELISA) kit (ITEH0269) and Immunotag™ Human ADP (adiponectin) ELISA kit (ITEH2593). The levels were correlated with the clinical parameters. Results: There were an increase in the mean adiponectin level and a decrease in the mean resistin level at the end of periodontal therapy. Conclusions: Adiponectin which is an anti-inflammatory component was found to increase after periodontal therapy, and resistin which is an inflammatory component has been decreased after periodontal therapy.
format	article
author	P Fairlin S A Jacob Raja Johnson Raja James Tamil Selvan Kumar Ravi Shankar S Divya
author_facet	P Fairlin S A Jacob Raja Johnson Raja James Tamil Selvan Kumar Ravi Shankar S Divya
author_sort	P Fairlin
title	Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
title_short	Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
title_full	Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
title_fullStr	Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
title_full_unstemmed	Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
title_sort	evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: a clinico-biochemical study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/4a2fb6588c0e4d8281fc3b484a7ddac1
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Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study

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