Adrenal hormones mediate disease tolerance in malaria

Adrenal hormones mediate disease tolerance in malaria

Disease tolerance mechanisms counter the negative effects of infection without decreasing the pathogen load. Here, the authors show that in mouse models of malaria, such disease tolerance can be conferred by adrenal hormones, by preventing excessive inflammation and hypoglycemia.

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Bibliographic Details
Main Authors: Leen Vandermosten, Thao-Thy Pham, Sofie Knoops, Charlotte De Geest, Natacha Lays, Kristof Van der Molen, Christopher J. Kenyon, Manu Verma, Karen E. Chapman, Frans Schuit, Karolien De Bosscher, Ghislain Opdenakker, Philippe E. Van den Steen
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/4a46f7525e7d4cd28340e26b10d771de
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