HIV-1 Uncoating and Reverse Transcription Require eEF1A Binding to Surface-Exposed Acidic Residues of the Reverse Transcriptase Thumb Domain
ABSTRACT Once HIV-1 enters a cell, the viral core is uncoated by a poorly understood mechanism and the HIV-1 genomic RNA is reverse transcribed into DNA. Host cell factors are essential for these processes, although very few reverse transcription complex binding host cell factors have been convincin...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/4a4d6ef69adc4a16b353fd6bc94bca5a |
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