Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus

Abstract The cuticular hydrocarbon (CHC) profile reflects the insects’ physiological states. These include age, sex, reproductive stage, and gravidity. Environmental factors such as diet, relative humidity or exposure to insecticides also affect the CHC composition in mosquitoes. In this work, the C...

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Autores principales:	Fabiola Claudio-Piedras, Benito Recio-Tótoro, Jorge Cime-Castillo, Renaud Condé, Massimo Maffei, Humberto Lanz-Mendoza
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4a5b42dc84e44d22aba021535c400ba6
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spelling	oai:doaj.org-article:4a5b42dc84e44d22aba021535c400ba62021-12-02T16:53:18ZDietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus10.1038/s41598-021-90673-x2045-2322https://doaj.org/article/4a5b42dc84e44d22aba021535c400ba62021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90673-xhttps://doaj.org/toc/2045-2322Abstract The cuticular hydrocarbon (CHC) profile reflects the insects’ physiological states. These include age, sex, reproductive stage, and gravidity. Environmental factors such as diet, relative humidity or exposure to insecticides also affect the CHC composition in mosquitoes. In this work, the CHC profile was analyzed in two Anopheles albimanus phenotypes with different degrees of susceptibility to Plasmodium, the susceptible-White and resistant-Brown phenotypes, in response to the two dietary regimes of mosquitoes: a carbon-rich diet (sugar) and a protein-rich diet (blood) alone or containing Plasmodium ookinetes. The CHCs were analyzed by gas chromatography coupled to mass spectrometry or flame ionization detection, identifying 19 CHCs with chain lengths ranging from 20 to 37 carbons. Qualitative and quantitative changes in CHCs composition were dependent on diet, a parasite challenge, and, to a lesser extent, the phenotype. Blood-feeding caused up to a 40% reduction in the total CHC content compared to sugar-feeding. If blood contained ookinetes, further changes in the CHC profile were observed depending on the Plasmodium susceptibility of the phenotypes. Higher infection prevalence caused greater changes in the CHC profile. These dietary and infection-associated modifications in the CHCs could have multiple effects on mosquito fitness, impacts on disease transmission, and tolerance to insecticides.Fabiola Claudio-PiedrasBenito Recio-TótoroJorge Cime-CastilloRenaud CondéMassimo MaffeiHumberto Lanz-MendozaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fabiola Claudio-Piedras Benito Recio-Tótoro Jorge Cime-Castillo Renaud Condé Massimo Maffei Humberto Lanz-Mendoza Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
description	Abstract The cuticular hydrocarbon (CHC) profile reflects the insects’ physiological states. These include age, sex, reproductive stage, and gravidity. Environmental factors such as diet, relative humidity or exposure to insecticides also affect the CHC composition in mosquitoes. In this work, the CHC profile was analyzed in two Anopheles albimanus phenotypes with different degrees of susceptibility to Plasmodium, the susceptible-White and resistant-Brown phenotypes, in response to the two dietary regimes of mosquitoes: a carbon-rich diet (sugar) and a protein-rich diet (blood) alone or containing Plasmodium ookinetes. The CHCs were analyzed by gas chromatography coupled to mass spectrometry or flame ionization detection, identifying 19 CHCs with chain lengths ranging from 20 to 37 carbons. Qualitative and quantitative changes in CHCs composition were dependent on diet, a parasite challenge, and, to a lesser extent, the phenotype. Blood-feeding caused up to a 40% reduction in the total CHC content compared to sugar-feeding. If blood contained ookinetes, further changes in the CHC profile were observed depending on the Plasmodium susceptibility of the phenotypes. Higher infection prevalence caused greater changes in the CHC profile. These dietary and infection-associated modifications in the CHCs could have multiple effects on mosquito fitness, impacts on disease transmission, and tolerance to insecticides.
format	article
author	Fabiola Claudio-Piedras Benito Recio-Tótoro Jorge Cime-Castillo Renaud Condé Massimo Maffei Humberto Lanz-Mendoza
author_facet	Fabiola Claudio-Piedras Benito Recio-Tótoro Jorge Cime-Castillo Renaud Condé Massimo Maffei Humberto Lanz-Mendoza
author_sort	Fabiola Claudio-Piedras
title	Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
title_short	Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
title_full	Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
title_fullStr	Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
title_full_unstemmed	Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus
title_sort	dietary and plasmodium challenge effects on the cuticular hydrocarbon profile of anopheles albimanus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4a5b42dc84e44d22aba021535c400ba6
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Dietary and Plasmodium challenge effects on the cuticular hydrocarbon profile of Anopheles albimanus

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