Reflectance Confocal Microscopy of Aging Skin and Skin Cancer

Skin aging is a complex process that causes morphologic variations. Some of these variations have been hypothesized to be involved in skin cancer development. This paper reviews current knowledge of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of th...

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Autores principales:	Stefania Guida, Giovanni Pellacani, Silvana Ciardo, Caterina Longo
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2021
Materias:	Skin aging skin cancer collagen blood vessels reflectance confocal microscopy Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/4a6210cdd9ca4b6daa100af49aeba206
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spelling	oai:doaj.org-article:4a6210cdd9ca4b6daa100af49aeba2062021-11-17T08:27:51ZReflectance Confocal Microscopy of Aging Skin and Skin Cancer10.5826/dpc.1103a682160-9381https://doaj.org/article/4a6210cdd9ca4b6daa100af49aeba2062021-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1620https://doaj.org/toc/2160-9381 Skin aging is a complex process that causes morphologic variations. Some of these variations have been hypothesized to be involved in skin cancer development. This paper reviews current knowledge of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of the technique are described, and the RCM features of healthy skin and skin cancer are briefly discussed. Moreover, the RCM features at different layers of young and elderly skin are described, as are the variations that occur with passing years and in relation to sun exposure that contribute to photoaging and the development of skin cancer. RCM enables the noninvasive evaluation, at quasi-histologic resolution, of aging-related skin changes, some of which are shared with skin cancer; this ability helps avoid skin biopsy. Further research is needed to understand the relation between skin aging and skin cancer development. Stefania GuidaGiovanni PellacaniSilvana CiardoCaterina LongoMattioli1885articleSkin agingskin cancercollagenblood vesselsreflectance confocal microscopyDermatologyRL1-803ENDermatology Practical & Conceptual (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Skin aging skin cancer collagen blood vessels reflectance confocal microscopy Dermatology RL1-803
spellingShingle	Skin aging skin cancer collagen blood vessels reflectance confocal microscopy Dermatology RL1-803 Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
description	Skin aging is a complex process that causes morphologic variations. Some of these variations have been hypothesized to be involved in skin cancer development. This paper reviews current knowledge of the features of aged skin as seen with reflectance confocal microscopy (RCM). Basic principles of the technique are described, and the RCM features of healthy skin and skin cancer are briefly discussed. Moreover, the RCM features at different layers of young and elderly skin are described, as are the variations that occur with passing years and in relation to sun exposure that contribute to photoaging and the development of skin cancer. RCM enables the noninvasive evaluation, at quasi-histologic resolution, of aging-related skin changes, some of which are shared with skin cancer; this ability helps avoid skin biopsy. Further research is needed to understand the relation between skin aging and skin cancer development.
format	article
author	Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo
author_facet	Stefania Guida Giovanni Pellacani Silvana Ciardo Caterina Longo
author_sort	Stefania Guida
title	Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
title_short	Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
title_full	Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
title_fullStr	Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
title_full_unstemmed	Reflectance Confocal Microscopy of Aging Skin and Skin Cancer
title_sort	reflectance confocal microscopy of aging skin and skin cancer
publisher	Mattioli1885
publishDate	2021
url	https://doaj.org/article/4a6210cdd9ca4b6daa100af49aeba206
work_keys_str_mv	AT stefaniaguida reflectanceconfocalmicroscopyofagingskinandskincancer AT giovannipellacani reflectanceconfocalmicroscopyofagingskinandskincancer AT silvanaciardo reflectanceconfocalmicroscopyofagingskinandskincancer AT caterinalongo reflectanceconfocalmicroscopyofagingskinandskincancer
_version_	1718425795619192832

Reflectance Confocal Microscopy of Aging Skin and Skin Cancer

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